Regeneration of lost periodontal tissue is the ultimate goal of periodontal treatment, which is of great significance for the clinical improvement of lesions, the long-term survival of teeth and the satisfaction of aesthetic requirements. In recent years, with the development of clinical technology and medical instruments, in order to achieve better interdental tissue regeneration and aesthetic effect, researchers have innovated and improved the periodontal regeneration procedures through various techniques, preserving interdental tissues, improving the primary wound healing quality and reducing gingival recession. This review describes the development and characteristics of various papilla preservation procedures in periodontal tissue regeneration, including traditional papilla preservation flap, minimally invasive papilla preservation technique, entire papilla preservation technique and papilla preservation combined with soft tissue augmentation and focuses on the indications, incision design, and clinical benefits of these approaches in order to provide clinicians with more options for developing personalized treatments.
