植物乳杆菌漱口水防龋效果的初步研究

doi:10.13591/j.cnki.kqyx.2025.11.009

Abstract

Abstract:

Objective To evaluate the inhibitory effect of Lactobacillus plantarum mouthwash on the progression of caries in isolated teeth. Methods Human isolated teeth were infected with Streptococcus mutans solution, and treated with saline, commercial mouthwash, and Lactobacillus plantarum mouthwash, respectively, for 28 days. Tooth changes were recorded to assess their inhibitory effect on caries progression by light microscopy and scanning electron microscopy. Results Lactobacillus plantarum had an inhibitory effect on caries progression,with significant effects on deep dentinal caries in pit and fissure, and similar efficacy to commercial mouthwash on smooth surface caries. Calcium loss in dentin tubules was observed under an electron microscope, with Lactobacillus plantarum group less than commercial group and saline group. Conclusion Lactobacillus plantarum mouthwash can inhibit the growth of Streptococcus mutans and effectively prevent caries, particularly in controlling the progression of deep pit and fissure caries.

Key words: Lactobacillus plantarum, caries, Streptococcus mutans, mouthwash, scanning electron microscopy

CLC Number:

R781.1

ZHU Han, FANG Yuankai, CAO Haitao, WU Rong, QIU Dihong. Preliminary research on the anti-caries effect of Lactobacillus plantarum mouthwash[J]. Stomatology, 2025, 45(11): 849-853.

Figures/Tables 6

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References 25

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龋损部位	A				B				C				D
龋损部位	A1	A2	A3	A4	B1	B2	B3	B4	C1	C2	C3	C4	D1	D2	D3	D4
颊面	2	2	2	2	4	2	2	2	2	2	2	2	6	4	4	4
舌面	2	2	2	2	2	2	2	2	2	2	2	2	6	4	4	4
邻面	2	2	1	1	6	2	2	4	4	3	2	5	8	8	8	8

分组	计分
分组	E	Ds	Dm	Dx
阳性对照组	17.20±8.92	12.39±3.86	8.51±7.01	4.01±3.38
阴性对照组	6.82±6.54	5.21±4.63	3.27±3.28	1.26±2.52
实验组	7.89±4.13	4.01±2.42	1.58±0.98	0.23±0.46
空白组	4.75±4.18	0	0	0

Preliminary research on the anti-caries effect of Lactobacillus plantarum mouthwash

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