Channel: Basic Research http://www.stomatology.cn/jwk3_kqyx/kqyx EN-US http://www.stomatology.cn/jwk3_kqyx/kqyx/EN/1003-9872/current.shtml http://www.stomatology.cn/jwk3_kqyx/kqyx 1003-9872 http://www.stomatology.cn/jwk3_kqyx/kqyx/EN/abstract/abstract6724.shtml http://www.stomatology.cn/jwk3_kqyx/kqyx/EN/abstract/abstract6725.shtml http://www.stomatology.cn/jwk3_kqyx/kqyx/EN/abstract/abstract6726.shtml http://www.stomatology.cn/jwk3_kqyx/kqyx/EN/abstract/abstract6727.shtml 0.05). The Shanno index, Chao index, and ACE index were higher in intraductal saliva than oral cavity (P<0.05). Intraductal microbiota structure comparison showed that Fusobacterium in the experimental group was significantly higher than the control group (p <0.05). At genus level, Prevotella, Porphyromonas and Neisseria were significantly reduced in the experimental group (P<0.05). The comparison of bacterial structures in the oral cavity showed that at the phylum level, Proteobacteria was significantly higher in the experimental group than in the control group (P<0.05). At genus level, Proteus, Streptococcus, and Veillonococcus in the experimental group were significantly lower than the control group (P<0.05). Conclusions The structure and diversity of microbiota in the stone sample are similar to salivary gland duct. The microbial diversity in the salivary gland duct is significantly higher than oral cavity. There is a significant difference in the microbial community between sialolithiasis patients and controlled subjects. There is a dysbacteriosis in the oral and salivary gland ducts of sialolithiasis patients.]]> http://www.stomatology.cn/jwk3_kqyx/kqyx/EN/abstract/abstract6728.shtml