血清锌含量与复发性口腔溃疡及味觉的相关性研究

›› 2015, Vol. 35 ›› Issue (6): 452-455.

血清锌含量与复发性口腔溃疡及味觉的相关性研究

茅海东¹,程剑¹,石炜²

1. 南京鼓楼医院集团仪征医院
2. 江苏省口腔医院

收稿日期:2014-12-22 修回日期:2015-02-11 出版日期:2015-06-28 发布日期:2015-07-01
通讯作者: 茅海东 E-mail:maoshan0@163.com

The relationship between serum zinc concentration and recurrent oral ulcer and taste

Received:2014-12-22 Revised:2015-02-11 Online:2015-06-28 Published:2015-07-01

摘要/Abstract

摘要： 摘要目的：探讨血清锌含量与复发性口腔溃疡（复发性阿弗它溃疡，RAU）及味觉的相关性。方法：选取2013年1月至2014年1月我院口腔科门诊就诊的40例RAU患者作为观察组，另选取同期我院体检的健康体检者50例为对照组，采用原子吸收分光光度法检测两组受试者的血清锌含量，并使用浓度为0.1%~0.6%的6组盐水，检测两组受试者的味觉，记录味觉积分。结果：观察组患者血清锌含量为76.74±8.28ug/dL，明显低于对照组的81.52±7.41ug/dL，差异具有统计学意义（P<0.01）；观察组的味觉积分为17.36±5.68分，与对照组（16.26±4.48分）相比，差异无统计学意义（P>0.05）。观察组及对照组中男性血清锌含量均高于女性，味觉积分均也明显高于女性，差异具有统计学意义（P<0.05）。重型RAU患者的血清锌含量明显低于轻型RAU患者，差异具有统计学意义（P<0.05）；味觉积分比较，重型明显高于轻型，差异具有统计学意义（P<0.05）。Pearson相关性分析显示，血清锌含量与年龄无相关性，血清锌含量与味觉积分无相关性，味觉积分与年龄呈正相关。结论：血清锌含量降低可能是成人RAU发病的原因之一，血清锌含量与味觉无相关性。

关键词: 复发性口腔溃疡, 血清锌, 味觉

Abstract: Abstract： Objective: To investigate the relationship between serum zinc concentration and recurrent apthous ulcer (RAU) and taste. Methods: From Jan 2013 to Jan 2014, forty patients of RAU were collected as the observation group. Meanwhile, 50 health examinees in our hospital were taken as the control group. The serum zinc concentration was determined by atomic absorption spectrophotometry，and a taste test for both group. Results: The serum zinc level of observation group was significantly lower than control group (P<0.01). The scores of taste test between observation group and control group was not statistically significant (P>0.05). The serum zinc level and the scores of taste test in males were higher than females in each group. Patients with MiRAU had a lower level of serum zinc than patients with MaRAU (P<0.05). The scores of taste test in patients with MiRAU were higher than that in patients with MaRAU (P<0.05). The Pearson correlational analyses showed serum levels of zinc have no relation with age (P>0.05), scores of taste test grows with age (P<0.05), serum zinc levels have no relation with taste scores (P>0.05). Conclusion：The cause of RAU has a relationship with zinc deficiency. The serum zinc level has no reference with taste.

Key words: recurrent apthous ulcer, zinc deficiency, hypogeusia

中图分类号:

R781.51

茅海东程剑石炜. 血清锌含量与复发性口腔溃疡及味觉的相关性研究[J]. 口腔医学, 2015, 35(6): 452-455.

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