›› 2014, Vol. 34 ›› Issue (6): 435-437.

• 基础与临床研究 • 上一篇    下一篇

预防腮腺术后Frey综合征的临床比较研究

周建华1,邱建忠2,陈正岗2,童磊1,3,王莉莉2   

  1. 1. 青岛市立医院
    2. 青岛市立医院口腔医疗中心
    3.
  • 收稿日期:2013-08-27 修回日期:2013-10-19 出版日期:2014-06-28 发布日期:2014-07-07
  • 通讯作者: 周建华 E-mail:zhoujhqd@126.com

Clinical comparative study of the different techniques to prevent Frey′s syndrome after parotidectomy

  • Received:2013-08-27 Revised:2013-10-19 Online:2014-06-28 Published:2014-07-07

摘要: 目的 评价腮腺肿瘤术后预防Frey综合征常见方法的效果。 方法 选择2005—2010年住院行腮腺浅叶或部分切除的患者153例,分为4组:A组(对照组)51例,传统的不保留腮腺咬肌筋膜手术;B组(保留咬肌筋膜组)18例,采取腮腺咬肌筋膜下翻瓣,保留腮腺咬肌筋膜手术;C组(胸锁乳突肌瓣组)23例,不保留腮腺咬肌筋膜,采取胸锁乳突肌瓣覆盖创面;D组(ADM组)61例,不保留腮腺咬肌筋膜,使用异种脱细胞真皮覆盖创面。所有术后患者随访,采取主观及客观评价方法对其预防Frey综合征的效果进行比较。 结果 A、B、C、D四组Frey综合征主观症状的发生率为39.22%(20/51)、5.56%(1/18)、13.04%(3/23)、4.92%(3/61);客观症状的发生率分别为72.55%(37/51)、16.67%(3/18)、17.39%(4/23)、8.20%(5/61);经统计学分析, B、C、D组与A组间Frey综合征发生率差异具有统计学意义(P<0.05),B、C、D组间两两比较Frey综合征发生率差异无统计学意义(P>0.05)。 结论 采用脱细胞真皮基质方法简单,对预防Frey综合征效果明显,值得临床广泛应用。

关键词: Frey’s征, 腮腺切除, 胸锁乳突肌瓣, 异种脱细胞真皮基质

Abstract: Objective To evaluate the clinical effects of parotid masseter fascia flap,sternocleidomastoid flap and heterogeneous acellular dermal matrix on preventing the incidence of Frey′s syndrome after parotidectomy. Methods  Having suffering from benign tumors in the parotid gland,153 patients who underwent partial parotidectomy in our hospital from 2005 to 2010 were included in this study.51 patients (control group) were treated with partial parotidectomy without parotid masseter fascia reserved.18 patients (parotid masseter fascia group) had parotid masseter fascia reserved in the partial parotidectomy.23 patients (sternocleidomastoid flap group) were treated with sternocleidomastoid flap in the partial parotidectomy.61 patients (ADM group) underwent insertion of H-ADM after parotidectomy.All the patients were inquired by questionnaire for subjective symptoms of Frey′s syndrome and objectively evaluated by Minor′s starch-iodine test.SPSS 17.0 software package was used for Chi-square test. Results  The incidences of subjective symptoms of Frey′s syndrome in four groups were respectively 39.22%(20/51)、5.56%(1/18)、13.04%(3/23)、4.92%(3/61)and the incidences of objective ones by starch-iodine testing were 72.55%(37/51)、16.67%(3/18)、17.39%(4/23)、8.20%(5/61)respectively.The difference between the four groups was statistically significant (P<0.05) while there was no statistically significant difference among B,C,D groups. Conclusions  Implanting ADM is an easy and effective way to prevent the incidence of Frey′s syndrome in the patients after partial parotidectomy,which is worth widespread use.

Key words: Frey's syndrome., parotidectomy, sternocleidomastoid flap, Heterogeneous acellular dermal matrix

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