›› 2017, Vol. 37 ›› Issue (1): 16-19.

• 基础研究 • 上一篇    下一篇

微创方法提高大鼠拔牙效率的初步研究

陈媛丽1,许广杰2,郭宇轩2,肖维维2,杨霞2,侯锐3,田磊2   

  1. 1. 第四军医大学口腔医院
    2. 陕西省西安市新城区长乐西路169号第四军医大学口腔医院
    3. 第四军医大学口腔医学院口腔外科
  • 收稿日期:2016-07-12 修回日期:2016-08-24 出版日期:2017-01-28 发布日期:2017-01-17
  • 通讯作者: 侯锐 E-mail:hourui@fmmu.edu.cn
  • 基金资助:
    国家自然科学基金;陕西省自然基金;军事口腔医学国家重点实验室的自主研究课题

Preliminary research on improving the extraction efficiency of rats by minimally invasive method

  • Received:2016-07-12 Revised:2016-08-24 Online:2017-01-28 Published:2017-01-17

摘要: 目的 研究改进大鼠微创拔牙方法后的拔牙效果。方法 将20只SD雌性大鼠随机分为两组,分别用微创方法(实验组)和常规方法(对照组)拔除两组左侧上、下颌6颗磨牙,观察术后大鼠存活情况、牙齿完整情况、拔牙区软组织的损伤情况。结果 采用微创方法拔牙后大鼠存活率提高,牙冠破碎牙根断裂的发生率下降,拔牙创周围软组织损伤程度轻。结论 微创拔牙方法为需要拔牙后建立大鼠模型的实验节省了时间和资源,有效保证了实验后续进行。

关键词: 动物模型, 拔牙, 微创, 大鼠

Abstract: Objective  To study the effect of minimally invasive tooth extraction in rats. Methods Twenty SD female rats were randomly divided into two groups,the left six molars were extracted by conventional methods(control group) and minimally invasive method(experimental group) respectively. Postoperative survival rates, teeth intactness and the injury of soft tissue in extraction sites were observed. Results Compared with control group, the rat survival rates increased in experimental group, the incidence of crown and root fracture decreased, and the degree of soft tissue injury in dental sockets were milder than the control group. Conclusion The minimally invasive extraction method can effectively save time and resources of animal experiments, which can ensure the following experiments to carry on smoothly.

Key words: animal model, extraction, micro-invasive, rats

中图分类号: