›› 2017, Vol. 37 ›› Issue (9): 849-853.

• 综述 • 上一篇    下一篇

双膦酸盐相关性颌骨坏死的发生机制与风险评估

李萌宇1,王绍义2   

  1. 1. 上海第九人民医院
    2. 上海交通大学医学院附属第九人民医院
  • 收稿日期:2017-02-13 修回日期:2017-04-07 出版日期:2017-09-28 发布日期:2017-09-22
  • 通讯作者: 李萌宇 E-mail:1014836807@qq.com
  • 基金资助:
    国家自然科学基金

Mechanism and risk assessment of bisphosphonaterelated osteonecrosis of the jaw

Meng YuLI1,   

  • Received:2017-02-13 Revised:2017-04-07 Online:2017-09-28 Published:2017-09-22
  • Contact: Meng YuLI E-mail:1014836807@qq.com

摘要: 双膦酸盐类(bisphosphonates,Bps)药物作为一种强有效的抗肿瘤和骨质疏松药广泛应用临床,但其引起的双膦酸盐相关性颌骨坏死(bisphosphonaterelated osteonecrosis of the jaw, BRONJ)患者日渐增多,严重影响患者生存质量,国内外尚无有效对策,成为当今口腔医学界急需克服的难题。该文对该疾病的最新研究进展及风险评估进行阐述,以期为临床提供帮助。

关键词: 双膦酸盐, 双膦酸盐相关性颌骨坏死, 风险评估

Abstract: Bisphosphonates, as strongly effective antitumor and antiosteoporosis drugs, are widely used in clinic, but the cases of bisphosphonaterelated osteonecrosis of the jaw (BRONJ) are increasing, seriously affecting the life quality of patients. It has become a difficult problem to overcome in the field of Oral Medicine all over the world since there has been no effective solution at home and abroad. This paper gives a review of the latest research progress and risk assessment of the BRONJ.

Key words: bisphosphonates, bisphosphonaterelated osteonecrosis of the jaw(BRONJ), risk assessment

中图分类号: