›› 2015, Vol. 35 ›› Issue (6): 487-489.

• 综述 • 上一篇    下一篇

白细胞介素17与牙周炎相关性的研究进展

刘引1,高涵2,于海蛟1,周岳1,申玉芹1,林崇韬1   

  1. 1. 吉林大学口腔医学院
    2. 吉林大学口腔医学院牙周病科
  • 收稿日期:2014-12-18 修回日期:2015-01-27 出版日期:2015-06-28 发布日期:2015-07-01
  • 通讯作者: 林崇韬 E-mail:linct@jlu.edu.cn
  • 基金资助:
    国家自然科学基金

Research progress of correlations between IL-17 and periodontitis

  • Received:2014-12-18 Revised:2015-01-27 Online:2015-06-28 Published:2015-07-01

摘要: 牙周炎是由牙周致病菌所致的牙周组织慢性炎症性,破坏性疾病。IL-17是一种主要由T细胞产生的促炎因子,参与牙周炎的发生、发展,并可能与牙周炎严重性相关。本文就IL-17参与牙周炎症免疫应答反应及牙槽骨吸收的机制做一综述,旨在阐明IL-17参与牙周疾病的研究现状。

关键词: IL-17, 牙周炎, 牙槽骨吸收

Abstract: Periodontitis is a chronic inflammatory and destruction disease caused by periodontal pathogens in the surrounding periodontal tissues.The pro-inflammatory cytokine IL-17, mainly produced by T cells ,which involved in the occurrence and development of periodontitis and this may be associated with disease severity.In this artical, we will review the inflammatory immune response and the mechanisms of alveolar bone absorption induced by IL-17 to illustrate the current research status of IL - 17 in periodontal disease.

Key words: IL-17, Periodontitis, Alveolar bone absorption

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