炎症微环境对牙周组织再生的影响

›› 2015, Vol. 35 ›› Issue (9): 786-788.

炎症微环境对牙周组织再生的影响

廖蔚文¹,宋忠臣²,束蓉²

1. 上海第九人民医院
2. 上海交通大学医学院附属第九人民医院

收稿日期:2015-03-09 修回日期:2015-04-30 出版日期:2015-09-28 发布日期:2015-09-14
通讯作者: 束蓉 E-mail:shurong123@hotmail.com
基金资助:
国家自然科学基金;国家自然科学基金

The effects of inflammatory microenvironment on regeneration of periodontal tissue

Received:2015-03-09 Revised:2015-04-30 Online:2015-09-28 Published:2015-09-14

摘要/Abstract

摘要： 慢性牙周炎是一种以牙周组织破坏为特征的慢性炎症性疾病。牙周病的最终治疗目的是牙周组织再生。而牙周炎时形成的局部炎症微环境，不仅造成牙周组织的破坏，而且会影响牙周组织再生过程，比如影响牙周膜干细胞的增殖分化以及生长因子的作用等。本文就炎症微环境对牙周组织再生的影响作一综述。

关键词: 炎症微环境, 牙周组织再生, 釉基质蛋白, 牙周膜干细胞, 骨髓间充质干细胞

Abstract: Chronic periodontitis is a kind of chronic inflammatory disease characterized by periodontal tissue damage.The ultimate therapeutic aim of periodontal disease is to obtain periodontal tissue regeneration.The local inflammatory microenvironment caused by periodontal disease not only leads to periodontal tissue damage,but also affects the process of periodontal regeneration.For example,it can affect the proliferation and differentiation of periodontal ligament stem cells and stifle the function of growth factors.This review discussed the effects of the inflammatory microenvironment on the regeneration of periodontal tissue.

Key words: inflammatory microenvironment, periodontal regeneration, enamel matrix protein, periodontal ligament stem cells, bone marrow mesenchymal stem cells

中图分类号:

R780.2

廖蔚文宋忠臣束蓉. 炎症微环境对牙周组织再生的影响[J]. 口腔医学, 2015, 35(9): 786-788.

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