种植失败原因分析

doi:10.13591/j.cnki.kqyx.2023.01.003

口腔医学 ›› 2023, Vol. 43 ›› Issue (1): 18-23.doi: 10.13591/j.cnki.kqyx.2023.01.003

种植失败原因分析

林国芬,许杨波,王思源,林梦娜,何福明()

浙江大学医学院附属口腔医院修复科·浙江大学口腔医学院·浙江省口腔疾病临床医学研究中心·浙江省口腔生物医学研究重点实验室·浙江大学癌症研究院,浙江杭州(310000

修回日期:2022-11-09 出版日期:2023-01-28 发布日期:2023-01-11
通讯作者: 何福明 E-mail:hfm@zju.edu.cn
作者简介:何福明,教授,主任医师,博士,博士生导师。浙江大学医学院附属口腔医院(浙江省口腔医院)口腔修复学科主任。中华口腔医学会口腔修复专委会常委,中华口腔医学会口腔材料学专委会委员,浙江省口腔医学会常务理事,浙江省口腔医学会口腔修复学专委会副主任委员,浙江省口腔医学会口腔种植专委会委员,国际牙医学院(ICD)院士,国际口腔种植组织(ITI)会员,美国骨性结合学会(AO)会员,2011年度浙江省“151人才”工程第三层次培养人员。加拿大多伦多大学牙学院访问学者。近5年主持6项国家级和省级课题,1项教改课题、1个MOOC项目,拥有多项国家发明专利,多次获得中华口腔医学会、省科技厅等学术奖励,2020年度浙江省卫生创新人才,近5年以第一作者或通信作者在国内外发表包括SCI论文30余篇。专业方向:长期从事种植体表面改性、骨结合机制的研究,国产ZDI种植系统研发及生物学评价和产品更新研究,以及口腔种植修复的临床长期随访观察等方面研究,对牙齿美容修复、口腔种植修复、活动义齿修复、全口义齿修复等疑难病例有丰富的临床经验,尤其对无牙颌All-on-four种植修复、上颌窦内提升术及上颌窦外提升术、全口咬合重建,数字化修复等领域有独到的治疗理念。
基金资助:
国家自然科学基金(82271026);浙江省科学技术厅重点研发计划项目(2019C03081)

Analysis of causes for dental implant failure

LIN Guofen,XU Yangbo,WANG Siyuan,LIN Mengna,HE Fuming()

Department of Preventive Dentistry, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou 310000, China

Revised:2022-11-09 Online:2023-01-28 Published:2023-01-11
Contact: HE Fuming E-mail:hfm@zju.edu.cn

摘要/Abstract

摘要：

种植修复已逐渐成为牙列缺损或牙列缺失患者的首选治疗方式。近年来,不少研究都聚焦于种植失败的发生原因,不过其相关影响因素仍存在一定争议。患者因素(性别、年龄、吸烟、骨质疏松症、糖尿病、药物服用、牙周炎、磨牙症),临床条件(种植部位、种植区骨质、种植体尺寸)和医生因素(手术因素、修复因素)均会对种植体的失败与否造成影响。本文通过典型病例和文献回顾,对种植体失败的原因和影响因素作一述评,以期为临床操作提供一定指导。

关键词: 种植失败, 影响因素, 典型病例

Abstract:

The implant-supported prosthesis has gradually become the preferred treatment for patients with partial edentulous or complete edentulous. Causes for the implant failure have been discussed in the majority of studies conducted in recent years, while their risk factors are still controversial. Patient factors (gender, age, smoking, osteoporosis, diabetes, medication, periodontitis and bruxism), clinical parameters (implant area, bone quality, implant size) and doctor factors (surgical-related factors, prosthesis-related factors) will all affect implant failure. This article presents typical clinical cases and reviews the potential risk factors for dental implant failure, in order to provide guidance for clinical practice.

Key words: implant failure, risk factor, typical case

中图分类号:

R783.4

林国芬,许杨波,王思源,林梦娜,何福明. 种植失败原因分析[J]. 口腔医学, 2023, 43(1): 18-23.

LIN Guofen,XU Yangbo,WANG Siyuan,LIN Mengna,HE Fuming. Analysis of causes for dental implant failure[J]. Stomatology, 2023, 43(1): 18-23.

图/表 4

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参考文献 40

[1]	Brånemark PI, Hansson BO, Adell R, et al. Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period[J]. Scand J Plast Reconstr Surg Suppl, 1977, 16:1-132. pmid: 356184
[2]	Esposito M, Hirsch JM, Lekholm U, et al. Biological factors contributing to failures of osseointegrated oral implants. (Ⅰ). Success criteria and epidemiology[J]. Eur J Oral Sci, 1998, 106(1):527-551. doi: 10.1046/j.0909-8836..t01-2-.x pmid: 9527353
[3]	Buhara O, Pehlivan S. Estimating the importance of significant risk factors for early dental implant failure: A Monte Carlo simulation[J]. Int J Oral Maxillofac Implants, 2018, 33(1):161-168. doi: 10.11607/jomi.5802 pmid: 29340350
[4]	Lin GF, Ye SH, Liu FJ, et al. A retrospective study of 30, 959 implants:Risk factors associated with early and late implant loss[J]. J Clin Periodontol, 2018, 45(6):733-743. doi: 10.1111/jcpe.12898
[5]	Do TA, Le HS, Shen YW, et al. Risk factors related to late failure of dental implant: A systematic review of recent studies[J]. Int J Environ Res Public Health, 2020, 17(11):3931. doi: 10.3390/ijerph17113931
[6]	Clark D, Levin L. Dental implant management and maintenance:How to improve long-term implant success?[J]. Quintessence Int, 2016, 47(5):417-423.
[7]	Sailer I, Karasan D, Todorovic A, et al. Prosthetic failures in dental implant therapy[J]. Periodontol 2000, 2022, 88(1):130-144. doi: 10.1111/prd.12416
[8]	Chrcanovic BR, Albrektsson T, Wennerberg A. Dental implants inserted in male versus female patients:A systematic review and meta-analysis[J]. J Oral Rehabil, 2015, 42(9):709-722. doi: 10.1111/joor.12308 pmid: 25989467
[9]	Staedt H, Rossa M, Lehmann KM, et al. Potential risk factors for early and late dental implant failure:A retrospective clinical study on 9 080 implants[J]. Int J Implant Dent, 2020, 6(1):81. doi: 10.1186/s40729-020-00276-w
[10]	Moy PK, Medina D, Shetty V, et al. Dental implant failure rates and associated risk factors[J]. Int J Oral Maxillofac Implants, 2005, 20(4):569-577.
[11]	Doll C, Nack C, Raguse JD, et al. Survival analysis of dental implants and implant-retained prostheses in oral cancer patients up to 20 years[J]. Clin Oral Investig, 2015, 19(6):1347-1352. doi: 10.1007/s00784-014-1359-2
[12]	Srinivasan M, Meyer S, Mombelli A, et al. Dental implants in the elderly population:A systematic review and meta-analysis[J]. Clin Oral Implants Res, 2017, 28(8):920-930. doi: 10.1111/clr.12898
[13]	Park JC, Baek WS, Choi SH, et al. Long-term outcomes of dental implants placed in elderly patients:A retrospective clinical and radiographic analysis[J]. Clin Oral Implants Res, 2017, 28(2):186-191.
[14]	Dutta SR, Passi D, Singh P, et al. Risks and complications associated with dental implant failure:Critical update[J]. Natl J MaxillofacSurg, 2020, 11(1):14-19.
[15]	Chrcanovic BR, Kisch J, Albrektsson T, et al. Factors influencing early dental implant failures[J]. J Dent Res, 2016, 95(9):995-1002. doi: 10.1177/0022034516646098 pmid: 27146701
[16]	Naseri R, Yaghini J, Feizi A. Levels of smoking and dental implants failure:A systematic review and meta-analysis[J]. J ClinPeriodontol, 2020, 47(4):518-528.
[17]	Yu HC, Kim YK. Fractures of implant fixtures: A retroscccpective clinical study[J]. Maxillofac Plast Reconstr Surg, 2020, 42(1):13. doi: 10.1186/s40902-020-00258-3
[18]	Merheb J, Temmerman A, Rasmusson L, et al. Influence of skeletal and local bone density on dental implant stability in patients with osteoporosis[J]. Clin Implant Dent Relat Res, 2016, 18(2):253-260. doi: 10.1111/cid.12290
[19]	Temmerman A, Rasmusson L, Kübler A, et al. An open, prospective, non-randomized, controlled, multicentre study to evaluate the clinical outcome of implant treatment in women over 60 years of age with osteoporosis/osteopenia:1-year results[J]. Clin Oral Implants Res, 2017, 28(1):95-102.
[20]	Kudo GAH, Leme BG, et al. Dental implants in patients with osteoporosis:A systematic review with meta-analysis[J]. Int J Oral MaxillofacSurg, 2018, 47(4):480-491.
[21]	Ulmner M, Jarnbring F, Törring O. Osteonecrosis of the jaw in Sweden associated with the oral use of bisphosphonate[J]. J Oral Maxillofac Surg, 2014, 72(1):76-82. doi: 10.1016/j.joms.2013.06.221
[22]	Hintze G. Diabetes-komplikationen[J]. Dtsch Med Wochenschr, 2020, 145(22):1585. doi: 10.1055/a-1038-0298
[23]	Jiang X, Zhu YL, Liu ZY, et al. Association between diabetes and dental implant complications: A systematic review and meta-analysis[J]. Acta Odontol Scand, 2021, 79(1):9-18. doi: 10.1080/00016357.2020.1761031
[24]	Tawil G, Younan R, Azar P, et al. Conventional and advanced implant treatment in the type Ⅱ diabetic patient:Surgical protocol and long-term clinical results[J]. Int J Oral Maxillofac Implants, 2008, 23(4):744-752.
[25]	Keenan JR, Veitz-Keenan A. Antibiotic prophylaxis for dental implant placement?[J]. Evid Based Dent, 2015, 16(2):52-53. doi: 10.1038/sj.ebd.6401097 pmid: 26114790
[26]	Salgado-Peralvo AO, Mateos-Moreno MV, Velasco-Ortega E, et al. Preventive antibiotic therapy in bone augmentation procedures in oral implantology:A systematic review[J]. J Stomatol Oral Maxillofac Surg, 2022, 123(1):74-80.
[27]	French D, Larjava H, Ofec R. Retrospective cohort study of 4591 Straumann implants in private practice setting, with up to 10-year follow-up. Part 1:Multivariate survival analysis[J]. Clin Oral Impl Res, 2015, 26(11):1345-1354. doi: 10.1111/clr.12463
[28]	Salgado-Peralvo AO, Peña-Cardelles JF, Kewalramani N, et al. Is penicillin allergy a risk factor for early dental implant failure? A systematic review[J]. Antibiotics, 2021, 10(10):1227. doi: 10.3390/antibiotics10101227
[29]	Brignardello-Petersen R. Implants placed in patients with a history of aggressive periodontitis had high survival rates and low marginal bone loss[J]. J Am Dent Assoc, 2017, 148(4):e37. doi: 10.1016/j.adaj.2017.02.023 pmid: 28258710
[30]	Sgolastra F, Petrucci A, Severino M, et al. Periodontitis, implant loss and peri-implantitis. A meta-analysis[J]. Clin Oral Implants Res, 2015, 26(4):e8-e16.
[31]	Smith MM, Knight ET, Al-Harthi L, et al. Chronic periodontitis and implant dentistry[J]. Periodontol 2000, 2017, 74(1): 63-73. doi: 10.1111/prd.12190
[32]	Noda K, Arakawa H, Kimura-Ono A, et al. A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations[J]. J Prosthodont Res, 2015, 59(3):178-184. doi: 10.1016/j.jpor.2015.04.003 pmid: 26077377
[33]	Doll C, Nack C, Raguse JD, et al. Survival analysis of dental implants and implant-retained prostheses in oral cancer patients up to 20 years[J]. Clin Oral Investig, 2015, 19(6): 1347-1352. doi: 10.1007/s00784-014-1359-2
[34]	Sreenivasan PK, Prasad KVV. Distribution of dental plaque and gingivitis within the dental Arches[J]. J Int Med Res, 2017, 45(5):1585-1596. doi: 10.1177/0300060517705476 pmid: 28795618
[35]	Manzano G, Montero J, Martín-Vallejo J, et al. Risk factors in early implant failure:A meta-analysis[J]. Implant Dent, 2016, 25(2):272-280. doi: 10.1097/ID.0000000000000386
[36]	Olmedo-Gaya MV, Manzano-Moreno FJ, Cañaveral-Cavero E, et al. Risk factors associated with early implant failure:A 5-year retrospective clinical study[J]. J Prosthet Dent, 2016, 115(2):150-155. doi: 10.1016/j.prosdent.2015.07.020 pmid: 26545864
[37]	Baqain ZH, Moqbel WY, Sawair FA. Early dental implant failure: Risk factors[J]. Br J Oral Maxillofac Surg, 2012, 50(3):239-243. doi: 10.1016/j.bjoms.2011.04.074 pmid: 21612850
[38]	Flanagan D. The case for smaller diameter implants[J]. J Oral Implantol, 2016, 42(6):517. doi: 10.1563/aaid-joi-D-16-00106 pmid: 27472266
[39]	Bocklage R. Biomechanical aspects of monoblock implant bridges for the edentulous maxilla and mandible: Concepts of occlusion and articulation[J]. Implant Dent, 2004, 13(1):49-53. pmid: 15017304
[40]	Gargallo-Albiol J, Salomó-Coll O, Lozano-Carrascal N, et al. Intra-osseous heat generation during implant bed preparation with static navigation: Multi-factor in vitro study[J]. Clin Oral Impl Res, 2021, 32(5):590-597. doi: 10.1111/clr.13728

种植失败原因分析

Analysis of causes for dental implant failure

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