治疗妊娠期牙周炎对孕妇妊娠结局的影响

›› 2015, Vol. 35 ›› Issue (10): 861-863.

治疗妊娠期牙周炎对孕妇妊娠结局的影响

姚本栈¹,黄慧¹,凌厉¹,刘静²,林杰³

1. 无锡市精神卫生中心
2. 无锡市妇幼保健医院
3. 无锡市101医院

收稿日期:2014-06-10 修回日期:2014-09-15 出版日期:2015-10-28 发布日期:2015-10-27
通讯作者: 姚本栈 E-mail:yaobenzhan@163.com
基金资助:
无锡市科技计划指导性项目

Effects of periodontal treatment on pregnant outcome in pregnant women with periodontitis

Received:2014-06-10 Revised:2014-09-15 Online:2015-10-28 Published:2015-10-27

摘要/Abstract

摘要： 目的　探讨牙周基础治疗对妊娠期牙周炎患者妊娠结局的影响。方法　选择进行孕检,经口腔科确诊为妊娠期牙周炎孕妇63名。牙周治疗组32例，在安全期内给予牙周基础治疗，对照组31例未接受牙周基础治疗。记录初始及妊娠32周时患者简化口腔卫生指数(OHI-S)、龈沟出血指数（SBI）、探诊深度(PD)和临床附着丧失(CAL)；在初始及妊娠32周时使用滤纸条法测量患者龈沟液（GCF）量，ELISA法测定龈沟液中白介素-1β（IL-1β）量；追踪妊娠结局。运用卡方检验，t检验和Spearman检验对数据进行分析。结果　①牙周治疗组妊娠32周检测的 OHI-S、SBI、PD、GCF量和IL-1β量较初始时有明显降低，且低于对照组同期（P＜0.05）；②牙周治疗组孕妇分娩孕周较对照组长，不良妊娠结局少于对照组（P＜0.05）；③孕妇妊娠32周检测的GCF量、IL-1β量与分娩孕周呈负相关关系（P＜0.05）。结论　孕期规范的牙周基础治疗有助于减少妊娠期牙周炎孕妇不良妊娠结局的可能性。

关键词: 妊娠期牙周炎, 牙周基础治疗, 早产

Abstract: Abstract: Objective To survey on effects of periodontal treatment on pregnant outcome in pregnant women with periodontitis. Methods 63 pregnant women diagnosed with maternal periodontitis were selected in Wuxi Maternal and Child Health-Care Hospital during 2012 April –December. The pregnant women were divided into periodontal treatment group (totally 32) and control group (totally 31). The OHI-S, SBI, PD , CAL were recorded at the beginning and at 32th gestational week; GCF volume was measured by filter strips and IL-1β was measured by ELISA at the same time; pregnant outcome was tracked. The result was analyzed with chi-square test, t test and Spearman correlation analysis. Results ①OHI-S, SBI, PD, GCF volume and IL-1β volume of periodontal treatment group at 32th gestational week were significantly lower than the beginning, and lower than the control group (P <0.05)；②Gestational age of periodontal treatment group was longer than the control group, and there were fewer adverse pregnancy outcomes in treatment group than in the control group (P <0.05)；③GCF volume and IL-1β volume at 32th gestational week and gestational age were negatively correlated (P <0.05). Conclusions Periodontal treatment may help reduce the incidence of the adverse pregnancy outcomes of maternal periodontitis women.

Key words: pregnancy periodontitis, periodontal treatment, preterm birth

中图分类号:

R780.1

姚本栈黄慧凌厉刘静林杰. 治疗妊娠期牙周炎对孕妇妊娠结局的影响[J]. , 2015, 35(10): 861-863.

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