芦荟在口腔临床医学应用中的研究新进展

摘要/Abstract

摘要： ［摘要］芦荟含有蒽醌类、糖类、有机酸、矿物质和维生素等多种有效成分，具有免疫调节、抗肿瘤、抗病毒、促进伤口愈合和抗炎等药理作用。芦荟及其提取物可用于诊疗口腔扁平苔藓、黏膜下纤维性变、口腔溃疡和牙周病等。芦荟在口腔临床医学的应用显示了其潜在的应用前景，但其机制还有待进一步阐明。

关键词: 芦荟, 药理作用, 口腔疾病, 临床应用

Abstract: Aloe contains a variety of active ingredients, including anthraquinone, sugars, organic acids, minerals and vitamins. These ingredients perform pharmacological effects such as immune regulation, anti-tumor, anti-virus, anti-inflammation and promoting wound healing. Aloe and its extracts can be used for diagnosis and treatment of oral lichen planus, oral submucous fibrosis, oral ulcer, periodontal diseases and so on. The application of aloe in dental clinical medicine shows its potential practical value, yet its mechanism remains to be elucidated.

Key words: Aloe, pharmacological effects, oral diseases, clinical application

中图分类号:

R917.799

张丽龙卉段开文. 芦荟在口腔临床医学应用中的研究新进展[J]. , 2017, 37(3): 285-288.

参考文献

[1]Radha MH,Laxmipriya NP.Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review[J].J Tradit Complement Med,2015,5(1):21-26
[2]Rodrguez RE,Darias Martn J,Daz Romero C.Aloe vera as a functional ingredient in foods[J].Crit Rev Food Sci Nutr,2010,50(4):305-326
[3]张吴琼，陈红杰，李郦芸，等.芦荟蒽醌类化合物的生物学功效[J].吉林医药学院学报,2013,34(1):52-55
[4]Hamman JH.Composition and applications of Aloe vera leaf gel[J].Molecules,2008,13(8):1599-616
[5]Mangaiyarkarasi SP,Manigandan T,Elumalai M,et al.Benefits of Aloe vera in dentistry[J].J Pharm Bioallied Sci,2015,7(Suppl 1):S255-259
[6]Gupta VK,Malhotra S.Pharmacological attribute of Aloe vera: Revalidation through experimental and clinical studies[J].Ayu,2012,33(2):193-196
[7]Babaee N,Zabihi E,Mohseni S,et al.Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis[J].Dent Res J Isfahan,2012,9(4):381-385
[8]Mansour G,Ouda S,Shaker A,et al.Clinical efficacy of new aloe vera- and myrrh-based oral mucoadhesive gels in the management of minor recurrent aphthous stomatitis: a randomized,double-blind,vehicle-controlled study[J].J Oral Pathol Med,2014,43(6):405-409
[9]Bhalang K,Thunyakitpisal P,Rungsirisatean N.Acemannan,a polysaccharide extracted from Aloe vera,is effective in the treatment of oral aphthous ulceration[J].J Altern Complement Med,2013,19(5):429-434
[10]Salazar-Sánchez N,López-Jornet P,Camacho-Alonso F,et al.Efficacy of topical Aloe vera in patients with oral lichen planus: a randomized double-blind study[J].J Oral Pathol Med,2010,39(10):735-740
[11]Mansourian A1,Momen-Heravi F,Saheb-Jamee M,et al.Comparison of aloe vera mouthwash with triamcinolone acetonide 01% on oral lichen planus: a randomized double-blinded clinical trial[J].. Am J Med Sci,2011,342(6):447-451
[12]Reddy RL,Reddy RS,Ramesh T,et al.Randomized trial of aloe vera gel vs triamcinolone acetonide ointment in the treatment of oral lichen planus[J].Quintessence Int,2012,43(9):793-800
[13]Patil BA,Bhaskar HP,Pol JS,et al.Aloe vera as cure for lichen planus[J].N Y State Dent J,2013,79(5):65-68
[14]Sudarshan R,Annigeri RG,Sree Vijayabala G.Aloe vera in the treatment for oral submucous fibrosis – A preliminary study[J].J Oral Pathol Med,2012,41(5):755-761
[15]Patil S,Al-Zarea BK,Maheshwari S,et al.Comparative evaluation of natural antioxidants spirulina and aloe vera for the treatment of oral submucous fibrosis[J].J Oral Biol Craniofac Res,2015,5(1):11-15
[16]Alam S,Ali I,Giri KY,et al.Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis[J].Oral Surg Oral Med Oral Pathol Oral Radiol,2013,116(6):717-724
[17]Ahmadi A.Potential prevention: Aloe vera mouthwash may reduce Radiation –induced oral mucositis in head and neck cancer patients[J].Chin J Integr Med,2012,18(3):635-640
[18]Sahebjamee M,Mansourian A,Mohammad MH,et al.Comparative Efficacy of Aloe vera and Benzydamine Mouthwashes on Radiation-induced Oral Mucositis: A Triple-blind,Randomised,Controlled Clinical Trial[J].Oral Health Prev Dent,2014,12(11):187-192
[19]López-Jornet P,Camacho-Alonso F,Molino-Pagan D.Prospective,randomized,double-blind,clinical evaluation of Aloe vera Barbadensis,applied in combination with a tongue protector to treat burning mouth syndrome[J].J Oral Pathol Med,2013,42(4):295-301
[20]Ajmera N,Chatterjee A,Goyal V.Aloe vera: It's effect on gingivitis[J].J Indian Soc Periodontol,2013,17:435-458
[21]Chandrahas B,Jayakumar A,Naveen A,et al.A randomized,double-blind clinical study to assess the antiplaque and antigingivitis efficacy of Aloe vera mouth rinse[J].J Indian Soc Periodontol,2012,16(4):543-548
[22]Bhat G,Kudva P,Dodwad V.Aloe vera: Nature's soothing healer to periodontal disease[J].J Indian Soc Periodontol,2011,15:205-209
[23]Boonyagul S,Banlunara W,Sangvanich P,et al.Effect of acemannan,an extracted polysaccharide from Aloe vera,on BMSCs proliferation,differentiation,extracellular matrix synthesis,mineralization,and bone formation in a tooth extraction model[J].Odontology,2014,102(2):310-317
[24]Badakhsh S,Eskandarian T,Esmaeilpour T.The use of aloe vera extract as a novel storage media for the avulsed tooth[J].Iran J Med Sci,2014,39(4):327-332
[25]George D,Bhat SS,Antony B.Comparative evaluation of the antimicrobial efficacy of Aloe vera tooth gel and two popular commercial toothpastes: An in vitro study[J].Gen Dent,2009,57(2):238-241
[26]Prabhakar AR,Karuna YM,Yavagal C,et al.Cavity disinfection in minimally invasive dentistry - comparative evaluation of Aloe vera and propolis: A randomized clinical trial[J].Contemp Clin Dent,2015,6(Suppl 1):S24-31
[27]Valera MC,Maekawa LE,de Oliveira LD,et al.In vitro antimicrobial activity of auxiliary chemical substances and natural extracts on Candida albicans and Enterococcus faecalis in root canals[J].J Appl Oral Sci,2013,21(2):118-123
[28]Fani M,Kohanteb J.Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria[J].J Oral Sci,2012,54(1):15-21