封闭术联合甲钴胺治疗原发性三叉神经痛的临床研究

›› 2018, Vol. 38 ›› Issue (3): 255-258.

封闭术联合甲钴胺治疗原发性三叉神经痛的临床研究

牛刚¹,林李嵩¹,吴烨¹,谢福平¹,游冬冬²

1. 福建医科大学附属口腔医院
2. 福建医科大学附属口腔医院颌面外科

收稿日期:2017-08-04 修回日期:2017-10-03 出版日期:2018-03-28 发布日期:2018-03-16
通讯作者: 牛刚 E-mail:274120724@qq.com
基金资助:
福建省教育厅课题，

A clinical study of blocking therapy combined with mecobalamin in the treatment for primary trigeminal neuralgia

Received:2017-08-04 Revised:2017-10-03 Online:2018-03-28 Published:2018-03-16
Contact: niu gang E-mail:274120724@qq.com

摘要/Abstract

摘要： 目的观察甲钴胺封闭治疗原发性三叉神经痛的临床疗效。方法我院2013年1月到2015年12月原发性三叉神经痛患者144例，男64例，女80例，年龄为38~80岁，随机分成实验组和对照组。实验组采用甲钴胺注射液1 mg和2％利多卡因2.0 mL混合液(共3.0 mL)疼痛区神经干封闭,对照组采用2%利多卡因3 mL疼痛区神经干封闭，每日1次，7～10 次为1疗程。结果实验组80例患者经过治疗后1年，临床治愈61例，好转10例，无效9例；对照组64例患者治疗后1年，临床治愈36例，好转15例，无效13例。治疗过程均未发生不良反应。结论甲钴胺封闭治疗原发性三叉神经痛疗效良好，适应证广，且无副作用。

关键词: 甲钴胺, 三叉神经痛, 封闭术

Abstract: Objective To assess the experiment effects of blocking therapy combined with mecobalamin on the treatment for patients with primary trigeminal neuralgia. Methods From February 2013 to December 2015， 80 cases (36 males and 44 females，aged from 38 to 82) , diagnosed as primary trigeminal neuralgia , were locally blocked in the neural stem of pain areas , with solution of 2% lidocaine 1.0mL and mecobalamin 2.0 mg (a total of 3.0 mL) ，1 time a day and 7～10 times were one course of treatment in our hospital. Results Among the 80 cases,61 cases were cured,10 cases were improved and 9 cases were in remission after the treatment. No side effects was detected during the whole treatment. Conclusion The blocking therapy combined with mecobalamin is an effective method with wide indications and without side effects in the treatment for trigeminal neuralgia.

Key words: mecobalamin , blocking therapy, trigeminal neuralgia

中图分类号:

R745.11

牛刚林李嵩吴烨谢福平游冬冬. 封闭术联合甲钴胺治疗原发性三叉神经痛的临床研究[J]. , 2018, 38(3): 255-258.

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