新型快速硬固型根尖倒充填材料的研究进展

摘要/Abstract

摘要： [摘要] 三氧化矿物聚合物 ( Mineral Trioxide Aggregate，MTA)是目前临床上常用的根尖倒充填材料，不仅具有良好的生物相容性和封闭性，而且具有很好抗菌和成骨效果。然而MTA存在着硬固时间长和操作性差的缺点。近年来，为缩短MTA的硬固时间，一些新型快速硬固型硅酸钙基根尖倒充填材料相继出现，本文将对这一类新型材料的种类和研究进展作一综述。

关键词: 三氧化矿物聚合物, 生物活性牙本质替代物Biodentine, 生物活性陶瓷材料iRoot FS

Abstract: Abstract：MTA (Mineral Trioxide Aggregate) is a widely used retrograde filling material in endodontics.It not only has good biocompatibility,good sealing ability,but also is antibacterial and hard tissue conductive.But it has two weeknesses:long setting time and inconvenience in operation.In recent years, there are a lot of studies of new fast setting calcium silicate-based retrograde filling materials aiming to shorten the setting time of MTA. This paper is a review on progresses in these new retrograde filling materials.

Key words: MTA, dentine restorative material Biodentine, bio-ceramic materials iRoot FS

中图分类号:

R783.1

屠美洁宿凌恺何福明邓淑丽. 新型快速硬固型根尖倒充填材料的研究进展[J]. 口腔医学, 2020, 40(1): 87-91.

参考文献 50

[1]	Kim S, Song M, Shin S J, et al.A Randomized Controlled Study of Mineral Trioxide Aggregate and Super Ethoxybenzoic Acid as Root-end Filling Materials in Endodontic Microsurgery: Long-term Outcomes[J].J Endod, 2016, 42(7):997-1002
[2]	Shinbori N, Grama A M, Patel Y, et al.Clinical Outcome of Endodontic Microsurgery That Uses EndoSequence BC Root Repair Material as the Root-end Filling Material[J].Journal of Endodontics, 2015, 41(5):607-612
[3]	Zhou W, Zheng Q, Tan X, et al.Comparison of Mineral Trioxide Aggregate and iRoot BP Plus Root Repair Material as Root-end Filling Materials in Endodontic Microsurgery: A Prospective Randomized Controlled Study[J].Journal of Endodontics, 2017, 43(1):1-6
[4]	路瑶, 姚丽萍, 卢志山.新型根管倒充填材料的研究进展[J].牙体牙髓牙周病学杂志, 2014, 24(8):495-497
[5]	Floratos S, Kim S.Modern Endodontic Microsurgery Concepts: A Clinical Update[J].Dental Clinics of North America, 2017, 61(1):81-91
[6]	Mk, U T, Me K, et al.The outcome of apical microsurgery using MTA as the root-end filling material: 2- to 6-year follow-up study[J].International endodontic journal, 2016, 49(3):245-54
[7]	Song M, Kang M, Kang D R, et al.Comparison of the effect of endodontic-periodontal combined lesion on the outcome of endodontic microsurgery with that of isolated endodontic lesion: survival analysis using propensity score analysis[J]. Clinical Oral Investigations, 2017: 1-8.
[8]	Wang Z H, Zhang M M, Wang J, et al.Outcomes of Endodontic Microsurgery Using a Microscope and Mineral Trioxide Aggregate: A Prospective Cohort Study[J].J Endod, 2017, 43(5):694-698
[9]	Ha W N, Bentz D P, Kahler B, et al.D90: The Strongest Contributor to Setting Time in Mineral Trioxide Aggregate and Portland Cement[J].J Endod, 2015, 41(7):1146-1150
[10]	Jang J H, Lee C O, Kim H J, et al.Enhancing Effect of Elastinlike Polypeptide-based Matrix on the Physical Properties of Mineral Trioxide Aggregate[J].J Endod, 2018, 44(11):1702-1708
[11]	S C, L S, J L, et al.Novel Fast-Setting Mineral Trioxide Aggregate: Its Formulation,Chemical-Physical Properties,and Cytocompatibility[J].ACS applied materials & interfaces, 2018, 10(24):20334-20341
[12]	Bn L, Hj K, Hs C, et al.Effects of mineral trioxide aggregate mixed with hydration accelerators on osteoblastic differentiation[J].Journal of endodontics, 2014, 40(12):2019-23
[13]	Jy K, Bn L, Hj S, et al.Biocompatibility of mineral trioxide aggregate mixed with hydration accelerators[J].Journal of endodontics, 2013, 39(4):497-500
[14]	Kb W, Sa S, Wg S.Effect of selected accelerants on the physical properties of mineral trioxide aggregate and Portland cement[J].Journal of endodontics, 2007, 33(10):1235-8
[15]	Th H, My S, Ct K, et al.The effect of setting accelerator on properties of mineral trioxide aggregate[J].Journal of endodontics, 2008, 34(5):590-3
[16]	Shie M Y, Huang T H, Kao C T, et al.The Effect of a Physiologic Solution pH on Properties of White Mineral Trioxide Aggregate[J].Journal of Endodontics, 2009, 35(1):98-101
[17]	P K, J H, Gn G, et al.The effects of various additives on setting properties of MTA[J].Journal of endodontics, 2006, 32(6):569-72
[18]	Dawood A E, Parashos P, Wong R H, et al.Calcium silicate-based cements: composition, properties, and clinical applications[J]. Journal of Investigative & Clinical Dentistry, 2015, 8(2): -.[J]., 2015, :1-15
[19]	Caron G, Azérad J, Faure M-O, et al.Use of a new retrograde filling material (Biodentine) for endodontic surgery: two case reports[J].International Journal of Oral Science, 2014, 6(4):250-253
[20]	Attik G N, Villat C, Hallay F, et al.In vitro biocompatibility of a dentine substitute cement on human MG63 osteoblasts cells: Biodentine? versus MTA(?)[J].International Endodontic Journal, 2015, 47(12):1133-1141
[21]	M C, R B, M C, et al.Biological and chemical-physical properties of root-end filling materials: A comparative study[J].Journal of conservative dentistry : JCD, 2015, 18(2):94-9
[22]	Gomes‐Corn, Eacute, Lio A L, et al.Bioactivity of MTA Plus, Biodentine and an experimental calcium silicate‐based cement on human osteoblast‐like cells[J]. International Endodontic Journal, 2017, 50(1).
[23]	Araújo L B, Cosmesilva L, Fernandes A P, et al.Effects of mineral trioxide aggregate, BiodentineTM and calcium hydroxide on viability, proliferation, migration and differentiation of stem cells from human exfoliated deciduous teeth[J]. Journal of Applied Oral Science, 2018, 26.
[24]	Khedmat S, Dehghan S, Hadjati J, et al.In vitrocytotoxicity of four calcium silicate-based endodontic cements on human monocytes,a colorimetric MTT assay[J].Restorative Dentistry & Endodontics, 2014, 39(3):149-154
[25]	Yuqing J, Qinghua Z, Xuedong Z, et al.A comparative study on root canal repair materials: a cytocompatibility assessment in L929 and MG63 cells[J].Thescientificworldjournal, 2014, 2014(12):463826-
[26]	Jung S, Mielert J, Kleinheinz J, et al.Human oral cells’ response to different endodontic restorative materials: an in vitro study[J].Head & Face Medicine, 2014, 10(55):1-9
[27]	Corral Nu?ez C M, Bosomworth H J, Field C, et al.Biodentine and mineral trioxide aggregate induce similar cellular responses in a fibroblast cell line[J].Journal of Endodontics, 2014, 40(3):406-411
[28]	Eppala J, Thumu J, Nagesh B, et al.quot;Evaluation of sealing ability of MM-MTA,Endosequence,and biodentine as furcation repair materials: UV spectrophotometric analysis"[J].Journal of Conservative Dentistry Jcd, 2014, 17(4):340-3
[29]	Agrafioti A, Tzimpoulas N, Chatzitheodoridis E, et al.Comparative evaluation of sealing ability and microstructure of MTA and Biodentine after exposure to different environments[J].Clinical Oral Investigations, 2016, 20(7):1-6
[30]	Aydemir S, Cimilli H, Gerni P M, et al.Comparison of the Sealing Ability of Biodentine, iRoot BP Plus and Mineral Trioxide Aggregate[J], 2016.
[31]	Samuel A, Asokan S, Priya P R G, et al.Evaluation of sealing ability of Biodentine? and mineral trioxide aggregate in primary molars using scanning electron microscope: A randomized controlledin vitrotrial[J].Contemporary Clinical Dentistry, 2016, 7(3):322-325
[32]	Han L, Okiji T.Uptake of calcium and silicon released from calcium silicate-based endodontic materials into root canal dentine[J].International Endodontic Journal, 2011, 44(12):1081-1087
[33]	Hitesh C, Harisha D, Annapoorna B M, et al.Comparative evaluation of sealing ability of glass ionomer-resin continuum as root-end filling materials: Anin vitrostudy[J].Journal of International Society of Preventive & Community Dentistry, 2015, 5(6):488-493
[34]	Soundappan S, Sundaramurthy J L, Raghu S, et al.Biodentine versus Mineral Trioxide Aggregate versus Intermediate Restorative Material for Retrograde Root End Filling: An Invitro Study[J].Journal of Dentistry, 2014, 11(2):143-9
[35]	Bolhari B, Yazdi K A, Sharifi F, et al.Comparative Scanning Electron Microscopic Study of the Marginal Adaptation of Four Root-End Filling Materials in Presence and Absence of Blood[J].Journal of Dentistry, 2015, 12(3):226-234
[36]	Kim J R, Nosrat A, Fouad A F.Interfacial characteristics of Biodentine and MTA with dentine in simulated body fluid[J].Journal of Dentistry, 2015, 43(2):241-247
[37]	Solanki N P, Venkappa K K, Shah N C.Biocompatibility and sealing ability of mineral trioxide aggregate and biodentine as root-end filling material: A systematic review[J].Journal of Conservative Dentistry Jcd, 2018, 21(1):10-15
[38]	Natale L C, Rodrigues M C, Xavier T A, et al.Ion release and mechanical properties of calcium silicate and calcium hydroxide materials used for pulp capping[J].International Endodontic Journal, 2015, 48(1):89-94
[39]	Chalas R, Mielko E, Zubrzycka-Wrobel J, et al.A chemical activity evaluation of two dental calcium silicate-based materials[J].Current Issues in Pharmacy & Medical Sciences, 2015, 28(2):89-91
[40]	Lv F, Zhu L, Zhang J, et al.Evaluation of the in vitro biocompatibility of a new fast-setting ready-to-use root filling and repair material[J]. International Endodontic Journal, 2016, 50(6).
[41]	谢克贤, 黎远皋, 张平.酸蚀处理对根尖倒充填材料封闭性的影响[J].北京大学学报：医学版, 2018, 50(1):69-72
[42]	Nair U, Ghattas S, Saber M, et al.A comparative evaluation of the sealing ability of 2 root-end filling materials: an in vitro leakage study using Enterococcus faecalis[J].Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics, 2011, 112(2):e74-e77
[43]	Leal F, De-Deus G, Brand?o C, et al.Similar sealability between bioceramic putty ready-to-use repair cement and white MTA[J].Brazilian Dental Journal, 2013, 24(4):362-366
[44]	王萌萌, 高国兵, 王颖.iRoot BP Plus 和 MTA 用于根尖手术的临床疗效比较[J].河南医学研究, 2018, 27(20):3664-3667
[45]	T L, J L, Y S, et al.Cytocompatibility of Biodentine and iRoot FS with human periodontal ligament cells: an in vitro study[J].International endodontic journal, 2018, 51(7):779-788
[46]	欧海强, 林正梅.根尖封闭性研究[J].中国实用口腔科杂志, 2017, 10(11):679-682
[47]	Askarinejad A, Pourkhorshidi A R, Parhizkar T.Evaluation the pozzolanic reactivity of sonochemically fabricated nano natural pozzolan[J].Ultrasonics Sonochemistry, 2012, 19(1):119-124
[48]	Y C, Sj P, Sh L, et al.Biological effects and washout resistance of a newly developed fast-setting pozzolan cement[J].Journal of endodontics, 2013, 39(4):467-72
[49]	Silva E J N L, Carvalho N K, Prado M, et al.Push-out Bond Strength of Fast-setting Mineral Trioxide Aggregate and Pozzolan-based Cements: ENDOCEM MTA and ENDOCEM Zr[J].Journal of Endodontics, 2017, 43(5):801-804
[50]	Mg G, P T, F S, et al.Development of the foremost light-curable calcium-silicate MTA cement as root-end in oral surgeryChemical-physical properties,bioactivity and biological behavior[J].Dental materials : official publication of the Academy of Dental Materials, 2011, 27(7):e134-e157