3D打印辅助手术治疗下颌骨缺损疗效的Meta分析

摘要/Abstract

摘要： 目的：分析研究3D打印技术应用于下颌骨缺损治疗的文献，评价3D打印技术对下颌骨缺损重建治疗效果的影响。方法：检索PubMed、MEDLINE、Cochrane图书馆、Embase、中国生物医学文献数据库、CNKI、万方数据库、维普资讯数据库正式发表的文献，检索起止时间为从建库至截止日期为2019年1月，收集应用3D打印技术于下颌骨缺损重建的临床对照试验，严格评价纳入研究的质量并提取数据，采用RevMan5.3软件进行Meta分析。结果：共纳入10篇临床对照研究，受试者共268例，其中3D打印组124例，非3D打印组144例；Meta分析显示，与传统的非3D打印技术辅助手术重建下颌骨相比，3D打印辅助技术组的术中组织缺血时间短[SMD=-39.78，95%CI为-57.85至-21.71，P＜0.01]、重建时间短[SMD=-31.90，95%CI为-43.12至-20.68，P＜0.01]、手术时间短[SMD=-76.93，95%CI为-106.93至-46.92，P＜0.01]，下颌骨重建精确性高。结论：下颌骨重建手术中应用3D打印技术具有缩短术中组织缺血与重建时间、手术时间短等优点，且能够提高下颌骨重建的精确性，提高手术效率和质量。

关键词: 下颌骨缺损, 下颌骨重建, 3D打印, Meta分析

Abstract: Objective: To evaluate the effect of 3D printing technology applied in the reconstruction of defected mandibular through the published literatures by Meta-analysis. Methods: The PubMed, MEDLINE, Cochrane library, Embase, CBM, CNKI and WanFang databases were searched from the date of database foundation to January 2019 to collect the controlled clinical trials in witch 3D printing technology was applied in mandibular reconstruction.Methodology quality of the trials was assessed critically and relative data were extracted, followed by analysis on the RevMan5.3 software. Results: Totally 10 controlled clinical trials including 268 cases were chosen.Among them,124 cases were assigned to the 3D printing technology group and 144 cases to the conventional group.The Meta-analysis results showed that the ischemic time [SMD=-39.78, 95%CI(-57.85,-21.71), P<0.01], reconstruction time[SMD=-31.90, 95%CI(-43.12,-20.68), P<0.01] and the operative time [SMD=-76.93, 95%CI(-106.93,-46.92), P<0.01] in the 3D printing technology were all lower than those in the conventional group, the accuracy of mandibular reconstruction was higher than the conventional group. Conclusion: 3D printing technology applied in the reconstruction of mandibular has the advantage of shorter ischemic time, reconstruction and operative time, and can improve the accuracy of mandibular reconstruction and improve the efficiency and quality of surgery.

Key words: Mandibular defect, Mandibular reconstruction, 3D printing, Meta analysis

中图分类号:

R782.4

魏婷. 3D打印辅助手术治疗下颌骨缺损疗效的Meta分析[J]. 口腔医学, 2020, 40(3): 232-238.

Ting WEI. Effect of 3D printing technology on mandibular reconstruction：A meta-analysis[J]. Stomatology, 2020, 40(3): 232-238.

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