种植体表面抗菌技术的分类与研究进展

摘要/Abstract

摘要： 随着种植体在口腔领域的广泛应用，口腔种植体相关的感染成为威胁种植体远期疗效的重大隐患。种植体表面的菌斑和生物膜与感染密切相关，一种有效的途径是通过种植体表面抗菌技术处理以防止微生物的聚集与粘附，本文就种植体表面抗菌技术的分类与研究进展作一综述。

关键词: 种植体, 抗菌涂层, 表面改性

Abstract: As dental implant is used widely during oral medicine. Infection around oral implants has been a hidden danger threatening longterm results. Plaque and biological membrane on the surface of dental implants are closely related to the infection. An effective way is to make surface treatment to prevent microorganism from gathering and adhesion. This passage will make a review about different kinds of surface treatment against bacteria and their research progress.

Key words: Dental implant, antimicrobial coating, surface modification

中图分类号:

R783.1

张晨秋王柏翔王慧明. 种植体表面抗菌技术的分类与研究进展[J]. 口腔医学, 2020, 40(3): 258-261.

参考文献 30

[1]	Hetrick, E.M. and MHSchoenfischReducing implant-related infections: active release strategies[J].Chemical Society Reviews, 2006, 35(9):780-780
[2]	Dunne W M.Bacterial adhesion: seen any good biofilms lately?[J].Clinical microbiology reviews, 2002, 15(2):155-166
[3]	Norowski, P.A. and JDBumgardnerBiomaterial and antibiotic strategies for peri-implantitis: A review[J].Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2009, 88B(2):530-543
[4]	冯玉霞.钛种植体表面载银抗茵涂层研究进展[J].中国实用口腔科杂志, 2015, 8(12):747-750
[5]	朱梓园, 张富强, 郑学斌.钛种植体载银抗菌羟基磷灰石涂层的制备及结构特征[J].上海口腔医学, 2006, 15(5):543-546
[6]	丁明超, 李德超.种植体表面制备载银涂层的方法[J].中国口腔种植学杂志, 2011, 16(2):139-143
[7]	卿云安, 李瑞延, 刘贯聪, 等.纳米银粒子改性种植体的研究进展[J].生物骨科材料与临床研究, 2017, 14(4):67-70
[8]	马千里等.载银二氧化钛纳米管阵列表面涂层的表面观察分析和细胞毒性评估[J].牙体牙髓牙周病学杂志, 2010, 20(09):492-497
[9]	封伟, 综述, 赵宝红, 等.微量元素在种植体骨结合中应用研究进展[J].中国实用口腔科杂志, 2011, 4(10):623-627
[10]	Feridoun P, Javad Y, Vahid J, et al.Overview of Nanoparticle Coating of Dental Implants for Enhanced Osseointegration and Antimicrobial Purposes[J].Journal of Pharmacy & Pharmaceutical Sciences, 2017, 20:148-160
[11]	封伟等.含锌活性涂层种植体材料对细菌黏附的影响[J].中华生物医学工程杂志, 2016, 21(1):37-40
[12]	Memarzadeh K, Sharili A S, Huang J, et al.Nanoparticulate zinc oxide as a coating material for orthopedic and dental implants[J].Journal of Biomedical Materials Research Part A, 2015, 103(3):981-989
[13]	李慕勤等.纯钛超声微弧氧化-化学镀铜涂层的制备及抗菌性[J].材料保护, 2016, 12:13-16
[14]	Yoshinari, M, et al.Influence of surface modifications to titanium on antibacterial activity in vitro[J].Biomaterials, 2001, 22(14):2043-2048
[15]	Wood N J, Jenkinson H F, Davis S A, et al.Chlorhexidine hexametaphosphate nanoparticles as a novel antimicrobial coating for dental implants[J].Journal of Materials Science Materials in Medicine, 2015, 26(6):201-201
[16]	李冠楠, 夏雪娟, 隆耀航, 等.抗菌肽的研究进展及其应用[J].动物营养学报, 2014, 26(1):17-25
[17]	Yazici, H, et al.Engineered Chimeric Peptides as Antimicrobial Surface Coating Agents toward Infection-Free Implants[J].ACS Applied Materials & Interfaces, 2016, 8(8):5070-5081
[18]	Chidambaranathan A S, Mohandoss K, Balasubramaniam M K.Comparative Evaluation of Antifungal Effect of Titanium,Zirconium and Aluminium Nanoparticles Coated Titanium Plates Against Calbicans[J].Journal of Clinical & Diagnostic Research Jcdr, 2016, 10(1):Z-C56
[19]	Colon G, Ward B C, Webster T J.Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2[J].Journal of Biomedical Materials Research Part A, 2006, 78(3):595-604
[20]	Tang T, Lin W T, Tan H L, et al.Inhibited bacterial biofilm formation and improved osteogenic activity on gentamicin-loaded titania nanotubes with various diameters[J].International Journal of Nanomedicine, 2014, 9:1215-1230
[21]	Radin S, Ducheyne P.Controlled release of vancomycin from thin sol–gel films on titanium alloy fracture plate material[J].Biomaterials, 2007, 28(9):1721-1729
[22]	Shi Z, NEOH, K.G,et alBacterial adhesion and osteoblast function on titanium with surface-grafted chitosan and immobilized RGD peptide[J].Journal of Biomedical Materials Research Part A, 2010, 86A(4):865-872
[23]	K?Licke T, Schierholz J, Schlegel U, et al.Effect on infection resistance of a local antiseptic and antibiotic coating on osteosynthesis implants: An in vitro and in vivo study[J].Journal of Orthopaedic Research, 2006, 24(8):1622-1640
[24]	Memarzadeh K, Sharili A S, Huang J, et al.Nanoparticulate zinc oxide as a coating material for orthopedic and dental implants[J].Journal of Biomedical Materials Research Part A, 2015, 103(3):981-989
[25]	Kazemzadeh-Narbat M, Lai B F L, Ding C, et al.Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections[J].Biomaterials, 2013, 34(24):5969-5977
[26]	Campbell A A, Song L, Li X S, et al.Development,characterization,and anti-microbial efficacy of hydroxyapatite-chlorhexidine coatings produced by surface-induced mineralization[J].Journal of biomedical materials research, 2000, 53(4):400-407
[27]	de Avila, ED, et al.Effect of UV-photofunctionalization on oral bacterial attachment and biofilm formation to titanium implant material[J].Biomaterials, 2015, 67:84-92
[28]	Kim M Y, Choi H, Lee J H, et al.UV Photofunctionalization Effect on Bone Graft in Critical One-Wall Defect around Implant: A Pilot Study in Beagle Dogs[J].BioMed Research International, 2016, 2016(5):1-9
[29]	张兰心, 王钦玥, 王莹雪.种植体多功能抗菌涂层的分类及进展[J].临床口腔医学杂志, 2017, 33(12):756-758
[30]	Curto B D, Brunella M F, Giordano C, et al.Decreased bacterial adhesion to surface-treated titanium[J].International Journal of Artificial Organs, 2005, 28(7):718-718