双膦酸盐在正畸治疗中的新进展与展望

›› 2020, Vol. 40 ›› Issue (3): 266-270.

双膦酸盐在正畸治疗中的新进展与展望

唐中元,姜欢,陈玉,胡敏

吉林大学

收稿日期:2019-08-15 修回日期:2019-10-01 出版日期:2020-03-28 发布日期:2020-03-31
通讯作者: 胡敏 E-mail:wl1963cc@126.com
基金资助:
国家自然科学基金-面上项目;省科技厅（基础处）自然科学基金

New progress and Prospect of bisphosphonate in orthodontic treatment

Received:2019-08-15 Revised:2019-10-01 Online:2020-03-28 Published:2020-03-31
Contact: Min Hu E-mail:wl1963cc@126.com

摘要/Abstract

摘要： 双膦酸盐（Bisphosphonates, BPs）可高效抑制骨吸收，不仅影响骨骼新陈代谢，而且对正畸治疗中的牙齿移动具有一定作用。最新研究表明，BPs 可通不同机制干扰破骨细胞的骨吸收，具有限制支抗牙齿的移动，减少牙根吸收，保持腭部快速扩弓疗效，加速颅面部牵张成骨的骨重建过程，并防止骨钉性感染与松动等诸多作用。本文就正畸治疗中的BPs作用机制、应用新进展和展望做归纳总结。

关键词: 双膦酸盐正畸牙根吸收腭部快速扩弓下颌牵张成骨

Abstract: Bisphosphonates （BPs）effectively inhibit bone resorption, not only affect bone metabolism, but also have a certain effect on tooth movement in orthodontic treatment. Recent new studies have shown that BPs interfere with bone resorption of osteoclasts through different mechanisms, restrict the movement of anchorage teeth, reduce root resorption, and maintain the effect of rapid palatal expansion. Therefore, BPs can accelerate the press of bone reconstruction in craniofacial stretching, and prevent the infection induced by bone nail and the tooth loosening. This article summarizes new progress and prospect of BPs regarding to the mechanism and applicationt in orthodontic treatment.

Key words: Bisphosphonates Orthodontic Root resorption Rapid palatal expansion Mandibular osteogenic distraction

中图分类号:

R783.5

唐中元姜欢陈玉胡敏. 双膦酸盐在正畸治疗中的新进展与展望[J]. 口腔医学, 2020, 40(3): 266-270.

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