[1]Urist MR.Bone: formation by autoinduction[J].Science,1965,150(3698):893-899
[2]Reddi AH,Reddi A.Bone morphogenetic proteins (BMPs): from morphogens to metabologens[J].Cytokine Growth Factor Rev,2009,20(5/6):341-342
[3]Bessa PC,Casal M,Reis RL.Bone morphogenetic proteins in t2/3 engineering: the road from laboratory to clinic,part II (BMP delivery)[J].J T2/3 Eng Regen Med,2008,2(2/3):81-96
[4]Zara JN,Siu RK,Zhang X,et al.High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo[J].T9/10 Eng Part A,2011,17(9/10):1389-1399
[5]Bessa PC,Casal M,Reis RL.Bone morphogenetic proteins in t1 engineering: the road from the laboratory to the clinic,part I (basic concepts)[J].J T1 Eng Regen Med,2008,2(1):1-13
[6]Isaacs MJ,Kawakami Y,Allendorph GP,et al.Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly[J].Mol Endocrinol,2010,24(7):1469-1477
[7]Zheng Y,Wu G,Zhao J,et al.rhBMP2/7 heterodimer: an osteoblastogenesis inducer of not higher potency but lower effective concentration compared with rhBMP2 and rhBMP7 homodimers[J].T3 Eng Part A,2010,16(3):879-887
[8]Zhao M,Zhao Z,Koh JT,et al.Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2,4,and 7[J].J Cell Biochem,2005,95(1):1-16
[9]潘秋辉，杨松海，孙奋勇.在CHO细胞中表达具有高效成骨活性的BMP-2/7异源二聚体[J].生物工程学报,2008,(03):473-479
[10]Zhu W,Rawlins BA,Boachie-Adjei O,et al.Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model[J].J Bone Miner Res,2004,19(12):2021-2032
[11]Zheng Y,Wang L,Zhang X,et al.BMP2/7 heterodimer can modulate all cellular events of the in vitro RANKL-mediated osteoclastogenesis,respectively,in different dose patterns[J].T5/6 Eng Part A,2012,18(5/6):621-630
[12]Koh JT,Zhao Z,Wang Z,et al.Combinatorial gene therapy with BMP2/7 enhances cranial bone regeneration[J].J Dent Res,2008,87(9):845-849
[13]Wang J,Zheng Y,Zhao J,et al.Low-dose rhBMP2/7 heterodimer to reconstruct peri-implant bone defects: a micro-CT evaluation[J].J Clin Periodontol,2012,39(1):98-105
[14]孙平，王利民，冯剑颖.骨钙素在BMP2/7异源二聚体诱导种植体周围骨缺损再生中的表达[J].中华老年口腔医学杂志,2011,(04):210-214
[15]Sun P,Wang J,Zheng Y,et al.BMP2/7 heterodimer is a stronger inducer of bone regeneration in peri-implant bone defects model than BMP2 or BMP7 homodimer[J].Dent Mater J,2012,31(2):239-248
[16]Sieber C,Kopf J,Hiepen C,et al.Recent advances in BMP receptor signaling[J].Cytokine Growth Factor Rev,2009,20(5/6):343-355
[17]Lavery K,Swain P,Falb D,et al.BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells[J].J Biol Chem,2008,283(30):20948-20958
[18]Miyazono K,Kamiya Y,Morikawa M.Bone morphogenetic protein receptors and signal transduction[J].J Biochem,2010,147(1):35-51
[19]Ehrlich M,Horbelt D,Marom B,et al.Homomeric and heteromeric complexes among TGF-beta and BMP receptors and their roles in signaling[J].Cell Signal,2011,23(9):1424-1432
[20]Sebald W,Nickel J,Zhang JL,et al.Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction[J].Biol Chem,2004,385(8):697-710
[21]Allendorph GP,Isaacs MJ,Kawakami Y,et al.BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors[J].Biochemistry,2007,46(43):12238-12247
[22]Saremba S,Nickel J,Seher A,et al.Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand[J].FEBS J,2008,275(1):172-183
[23]Buijs JT,van der Horst G,van den Hoogen C,et al.The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation[J].Oncogene,2012,31(17):2164-2174
[24]Pan Q,Yang S,Sun F.Expression of BMP-2/7 heterodimers with potent ability to stimulate osteogenic differentiation in CHO cells[J].Sheng Wu Gong Cheng Xue Bao,2008,24(3):473-479
[25]Butler S J,Dodd J.A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons[J].Neuron,2003,38(3):389-401
[26]Bragdon B,Moseychuk O,Saldanha S,et al.Bone morphogenetic proteins: a critical review[J].Cell Signal,2011,23(4):609-620
[27]Eivers E,Demagny H,De Robertis EM.Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad[J].Cytokine Growth Factor Rev,2009,20(5-6):357-365
[28]Zhu W,Kim J,Cheng C,et al.Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro[J].Bone,2006,39(1):61-71
[29]潘秋辉，杨松海，董群伟，等.BMP2/7异源二聚体调控CIZ的表达与自身活性的关系[J].中国生物工程杂志,2007,(09):14-18
|
苏公网安备32010602011670号