牙龈间充质干细胞递送支架载体的研究进展

doi:10.13591/j.cnki.kqyx.2022.02.015

摘要/Abstract

摘要： 组织工程技术通过利用支架材料、种子细胞、生长因子以达到修复或再生组织器官的目的。支架材料的作用是为种子细胞提供机械支撑并且保护细胞免受体内有害微环境的影响。因此,选择或制备适当的支架材料是组织工程中的关键一步。近年来,将支架材料和牙龈间充质干细胞(gingival mesenchymal stem cells,GMSCs)联合应用于组织工程的研究逐渐走向成熟。本文就组织工程中牙龈间充质干细胞递送支架载体的研究现状进行综述,以期为GMSCs组织工程递送支架载体材料的开发和选择提供思路。

关键词: 牙龈间充质干细胞, 支架材料, 天然高分子材料, 人工合成材料, 复合材料

Abstract: Tissue engineering technology uses scaffold materials, seed cells, and growth factors to achieve the purpose of repairing or regenerating tissues and organs. Scaffold provides mechanical support for seed cells and protects them from the harmful microenvironment in the body. Therefore, choosing or preparing appropriate scaffolds is a key step in tissue engineering. In recent years, the combined application of scaffold materials and gingival mesenchymal stem cells (GMSCs) in tissue engineering has gradually become mature. This article reviews the current research status of gingival mesenchymal stem cell delivery scaffold in tissue engineering, in order to provide ideas for the development and selection of delivery scaffolds for GMSCs tissue engineering.

Key words: gingival mesenchymal stem cells, scaffold material, natural polymers, synthetic polymers, composite material

中图分类号:

Q291

王法程, 郝鹏杰, 卢志山. 牙龈间充质干细胞递送支架载体的研究进展[J]. 口腔医学, 2022, 42(2): 170-175.

WANG Facheng, HAO Pengjie, LU Zhishan. Research progress of gingival mesenchymal stem cell delivery scaffolds[J]. Stomatology, 2022, 42(2): 170-175.

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