口腔医学 ›› 2022, Vol. 42 ›› Issue (11): 1019-1025.doi: 10.13591/j.cnki.kqyx.2022.11.012

• 病案分析 • 上一篇    下一篇

自身免疫性疾病累及颞下颌关节的15例病例临床分析及文献回顾

张梦杰, 陈敏洁   

  1. 上海交通大学医学院附属第九人民医院口腔外科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海(200011)
  • 收稿日期:2022-04-15 出版日期:2022-11-28 发布日期:2022-11-25
  • 通讯作者: 陈敏洁 E-mail:chenminjie00@126.com
  • 基金资助:
    上海市科学技术委员会“科技创新行动计划”医学创新研究专项(21Y11903500);上海交通大学医学院附属第九人民医院临床研究助推计划(JYLJ201903)

Temporomandibular disorders in patients with autoimmune diseases:Clinical analysis of 15 cases and literature review

ZHANG Mengjie, CHEN Minjie   

  1. Department of Oral, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology, Shanghai 200011, China
  • Received:2022-04-15 Online:2022-11-28 Published:2022-11-25

摘要: 目的 通过回顾分析,总结自身免疫性疾病导致颞下颌关节病变的临床和影像学特征,为早期明确诊断提供参考。方法 收集2014年12月至2021年6月于上海交通大学附属第九人民医院口腔外科就诊的15例自身免疫性疾病伴发颞下颌关节病变患者的病例资料,结合280例以往文献报道的病例分析其临床表现、影像学表现和治疗方法。结果 本文收集的15例患者中80%患者存在自身免疫性疾病病史,张口受限是患者最常见的主诉,其次为耳前疼痛。影像学检查可见无明显创伤诱因的关节上下腔积液、关节盘中带穿孔、无盘移位的髁突扁平状吸收、双侧囊内纤维性或骨性强直等表现。部分患者经抗风湿药物治疗疗效较好,4例进行了关节置换术,疗效稳定。结论 自身免疫性疾病所致的颞下颌关节病变患者在临床表现、影像学表现和治疗方式上均有特殊之处,尽早明确临床诊断以指导治疗方案的选择是必要的。

关键词: 颞下颌关节病变, 自身免疫性疾病, 颞下颌关节强直, 早期诊断

Abstract: Objective To summarize clinical and imaging findings of temporomandibular joint disorder caused by autoimmune diseases through retrospective analysis, so as to provide reference for early diagnosis. Methods Fifteen cases were collected in the Department of Oral Surgery, Shanghai Ninth People's Hospital from December, 2014 to June, 2021 and 280 cases were collected from literature. Clinical and imaging findings, together with treatment were analyzed. Results Among 15 cases collected in this article, 80% of the patients had a medical history of autoimmune diseases. Limitation of mouth opening was the most common chief complaints, followed by preauricular pain. Imaging findings were joint effusion at superior and inferior joint space without trauma, disc perforation at intermediate zone, flat absorption of condyle without disc displacement and bilateral intracapsular fibrous or bony ankylosis. Anti-rheumatic drugs showed good curative effects in some patients. Four patients underwent artificial TMJ replacement and the effects were stable. Conclusion TMJ disorders caused by autoimmune diseases differ from common TMJ disorders in clinical and imagine findings, as well as treatment, so early diagnosis is necessary to guide treatment planning.

Key words: TMJ disorder, autoimmune disease, TMJ ankylosis, early diagnosis

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