关键词: 艾司氯胺酮, 七氟烷, 儿童全麻, 牙科治疗, 血流动力学, 苏醒质量

Abstract:

Objective To analyze the effects of esmketamine and sevoflurane inhalation regimens on hemodynamics and recovery quality in children undergoing oral day surgery under general anesthesia. Methods A total of 136 children with caries were selected from our hospital from September 2020 to July 2021. All patients were expected to receive daytime dental treatment under general anesthesia and divided into a control group and a study group according to the random throwing method. The control group was given esketamine anesthesia, and the study group was given non-intubation sevoflurane inhalation anesthesia. The operation-related conditions, MAP, HR, SpO₂ indexes, CHIPPS score, PAED score and the incidence of anesthesia-related adverse events at each perioperative period were compared between the two groups. Results The onset time of anesthesia and the time of fully awake in the study group were shorter than those in the control group (P<0.05). There was no significant difference in the levels of MAP, HR and SpO₂ at T₁ between the two groups (P>0.05). MAP and HR were lower than those of the control group at T₂, and the difference was significant (P<0.05). There was no significant difference in SpO₂ levels at T₁, T₂, and T₃ (P>0.05). The CHIPPS and PAED scores of the study group were significantly lower than those of the control group at 15 and 30 min after awakening. In terms of adverse reactions, the total incidence of adverse reactions in the study group was 2.90% (2/68), which was lower than 11.76% (8/68) in the control group, with a significant difference (P<0.05). Conclusion Compared with esmketamine, sevoflurane has better value and safety in children undergoing oral day surgery under general anesthesia. It has rapid onset of anesthesia and good recovery quality. At the same time, it is beneficial to maintain hemodynamic stability, reduce the risk of anesthesia-related adverse reactions such as respiratory depression and vomiting, and has more promotional value.

Key words: esketamine, sevoflurane, children general anesthesia, dental treatment, hemodynamics, quality of recovery