机器人辅助定位平阳霉素注射治疗口腔颌面部脉管畸形的研究与应用

›› 2021, Vol. 41 ›› Issue (8): 699-703.

机器人辅助定位平阳霉素注射治疗口腔颌面部脉管畸形的研究与应用

邢乐君¹,陈飞²,贾婷婷³,孟凡皓³,周正³,乔波³,朱亮³,赵睿³,张海钟³

1. 中国人民解放军总医院第一医学中心（原301医院）
2. 中国人民解放军总医院第一医学中心
3. 解放军总医院（301医院）

收稿日期:2021-02-15 修回日期:2021-04-29 出版日期:2021-08-28 发布日期:2021-08-28
通讯作者: 张海钟 E-mail:zhang126301@126.com
基金资助:
科技部重大专项国家重点研发计划

The research and application of robot assisted positioning Pingyangmycin injection in the treatment of vascular malformation in oral and maxillofacial region

Received:2021-02-15 Revised:2021-04-29 Online:2021-08-28 Published:2021-08-28

摘要/Abstract

摘要： 目的　观察并研究机器人辅助定位下平阳霉素注射治疗口腔颌面部脉管畸形的临床疗效。方法：收集2017-2021年本院收治的有完整临床资料的共20例口腔颌面颈部脉管畸形患者进行回顾性分析，所有患者均采用机器人辅助定位平阳霉素药物注射治疗，观察并记录患者预后情况，复查颌面部增强CT或者MRI评价瘤体大小变化作为疗效评价指标。结果：20例患者均在机器人辅助下顺利完成手术，临床有效率95%，术后无药物不良反应发生。该技术手术安全性良好,充分发挥机器人定位准确的优势，采用退针给药的方法增强药物与脉管畸形病变内皮细胞作用面积，充分发挥药物治疗作用，缩短平阳霉素药物注射间隔时间。结论：机器人辅助定位并平阳霉素药物注射治疗脉管畸形安全有效，创伤小，精度高，可重复注射治疗，最大程度保留原始器官外形及功能发挥，临床应用价值高。

关键词: 机器人, 平阳霉素, 口腔颌面部, 脉管畸形 , 机器人辅助定位

Abstract: Objective To observe and study the clinical effect of Pingyangmycin injection under robot assisted localization in the treatment of vascular malformations in oral and maxillofacial region. Methods A total of 20 patients with vascular malformations in oral, maxillofacial and cervical region who had complete clinical data in our hospital from 2017 to 2021 were collected and analyzed retrospectively. All patients were treated with Pingyangmycin injection assisted by robot localization. The prognosis of patients was observed and recorded. The changes of tumor size were evaluated by maxillofacial enhanced CT or MRI as the evaluation index of curative effect. Results All the 20 patients successfully completed the operation with the assistance of robot. The clinical effective rate was 95%, and there was no adverse drug reaction after the operation. This technique has good safety, gives full play to the advantages of accurate robot positioning, enhances the interaction area between drugs and vascular malformation endothelial cells by using the method of needle withdrawal administration, gives full play to the role of drug therapy, and shortens the interval time of Pingyangmycin drug injection. Conclusion Robot assisted localization and Pingyangmycin drug injection in the treatment of vascular malformation is safe and effective, with small trauma and high precision, which can accept repeatable injection treatment and achieve the maximum preservation of the original organ shape and function, and has high clinical application value.

Key words: Robot, Pingyangmycin, oral and maxillofacial, vascular malformation, robot assisted localization

中图分类号:

R739.8

邢乐君陈飞贾婷婷孟凡皓周正乔波朱亮赵睿张海钟. 机器人辅助定位平阳霉素注射治疗口腔颌面部脉管畸形的研究与应用[J]. 口腔医学, 2021, 41(8): 699-703.

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