神经生长因子对促进种植体骨结合的研究进展

摘要/Abstract

摘要： ［摘要］神经生长因子（nerve growth factor，NGF）广泛分布于中枢神经系统及周围神经系统中，具有促进血管生长、创伤愈合和神经系统发育以及骨形成的作用。影响种植体骨结合稳定性的因素很多，种植体表面的性质是影响种植体骨结合的主要因素。NGF在种植体骨结合过程中具有增强骨细胞活性，促进成骨细胞分化、矿化，以及促进周围神经、血管形成的作用，它能够有效地促进种植体周围骨愈合，从而缩短口腔种植体骨愈合时间。本文就神经生长因子促进种植体骨结合的研究进展进行综述。

关键词: [关键词]神经生长因子, 种植体, 骨愈合

Abstract: Nerve growth factor (NGF) is widely distributed in the central nervous system and the peripheral nervous system. Many studies have found that NGF can promote blood vessel growth, wound healing, nerve system development and bone formation. Many factors can affect the stability of implant bone, among which implant surface property is the main one. In the process of implant?osseointegration, NGF can enhance the activity of osteocyte, promote osteoblast differentiation and mineralization, and improve the formation of peripheral nerve and blood vessel; it can also effectively promote healing of bone around the implant, and thus shorten the healing time of oral implant. This paper will review the role of NGF in promoting the?implant?osseointegration.

Key words: [key words] NGF, Implant, Bone healing

中图分类号:

R783.3

郑琛江银华. 神经生长因子对促进种植体骨结合的研究进展[J]. , 2018, 38(1): 83-86.

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