›› 2020, Vol. 40 ›› Issue (5): 411-415.

• 临床研究 • 上一篇    下一篇

颌骨囊性病变囊内压对开窗术后不同时间段体积缩小速度的影响

熊贤斌1,吴元元1,郑旸1,丁旭1,武和明1,吴煜农2,宋晓萌2   

  1. 1. 南京医科大学附属口腔医院
    2. 南京医科大学口腔医学院
  • 收稿日期:2019-11-04 修回日期:2020-01-03 出版日期:2020-05-26 发布日期:2020-06-08
  • 通讯作者: 宋晓萌 E-mail:sxm2081@163.com
  • 基金资助:
    国家自然科学基金;江苏省医学创新团队资助项目;江苏省高校优势学科建设工程

Effect of intracapsular pressure on the speed of shrinkage in different time periods after decompression

  • Received:2019-11-04 Revised:2020-01-03 Online:2020-05-26 Published:2020-06-08

摘要: [摘要] 目的 探讨颌骨囊性病变开窗减压后不同时间段体积缩小速度与囊内压之间的关系。方法 纳入南京医科大学附属口腔医院2018年4月到2019年10月影像学及病理学诊断为颌骨囊性病变且采用开窗减压术进行治疗的25例患者。术前使用压力传感器测量出囊内压力,使用Mimics 17.0软件分别在术前及术后3、6、12个月测量囊腔体积,计算囊性病变不同时间段的体积缩小速度(speed of shrinkage,SS,SS0-3:术后前3个月体积缩小速度;SS3-6:术后3到6月体积缩小速度;SS6-1:术后6~12个月体积缩小速度)。统计学方法采用方差分析及相关性检验,当P<0.05时差异有统计学意义。结果 SS0-3,SS3-6,SS6-1两两对比差异具有统计学意义。SS0-3与囊内压力成负相关(r=-0.5295,n=25,P<0.01),与年龄成负相关(r=-0.5866,n=25,P<0.01)。囊内压与术前囊腔的体积成负相关(r=-0.4487,n=25,P<0.05)。SS0-3与成人术前囊腔体积成正相关(r=0.4546,n=20,P<0.05)。结论 颌骨囊性病变开窗减压术后不同时间段体积缩小速度与囊内压力密切相关。

关键词: 颌骨囊性病变, 囊内压力, 开窗减压术, 体积缩小速度

Abstract: : Objective To investigate the relationship between the speed of shrinkage (SS) and the intracapsular pressure during indicated time after decompression. Methods Twenty-five patients who were diagnosed with cystic lesions of jaw bone by both imaging and pathological examination from April 2018 to October 2019 in the Affiliated Stomatological Hospital, Nanjing Medical University were enrolled in this study. Pressure sensors were utilized to measure the intracapsular pressure before operation. The volume of the cyst lesions was determined using mimics17.0 software before operation and 3, 6, 12 months after the surgery. Then the speed of shrinkage was calculated at different time periods (SS0-3: the rate of volume reduction in the first 3 months after surgery, SS3-6: the rate of volume reduction during 3 to 6 months after surgery, SS6-12: the rate of volume reduction during 6 to 12 months after surgery). The Student’s ANOVA and linear correction analysis were utilized to evaluate the statistical significance of the results and p < 0.05 was considered significant. Results 1. ANOVA statistical analysis showed that there were significant differences between SS0-3, SS3-6 and SS6-12. 2. SS0-3 was negatively correlated with intracapsular pressure (r = -0.5295, n=25, P<0.01). 3. SS0-3 was negatively correlated with age (r = -0.5866, n=25, P <0.01). 4. The intracapsular pressure was negatively associated with preoperative volume (r = -0.4487,n = 25,P<0.05). 5. The preoperative cystic volume of adults was positively correlated with SS0-3 (r =0.4546, n=20 ,P<0.05). Conclusion The intracapsular pressure of cystic lesions is closely related to the speed of shrinkage in different time periods after decompression.

Key words: cystic lesion of jaw bone , intracapsular pressure, decompression, speed of shrinkage

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