›› 2020, Vol. 40 ›› Issue (8): 754-757.

• 病案分析 • 上一篇    下一篇

原发于下颌骨内神经鞘瘤一例报告

刘福来1,李志萍2,孟箭2   

  1. 1. 蚌埠医学院
    2. 徐州市中心医院
  • 收稿日期:2019-04-25 修回日期:2019-07-11 出版日期:2020-08-29 发布日期:2020-08-28
  • 通讯作者: 李志萍 E-mail:jslzp@163.com

Intraosseous schwannomas of the mandible: A case report

  • Received:2019-04-25 Revised:2019-07-11 Online:2020-08-29 Published:2020-08-28

摘要: 神经鞘瘤大多数来源于周围神经鞘的施旺细胞,肿瘤多单发并且有包膜,生长较慢,与周围组织界限清楚,常为良性。头颈部神经鞘瘤主要发生于颅神经及周围神经,以头部、面部、舌部软组织最为常见;交感神经发生者较为少见,发生于下颌骨内的神经鞘瘤则更为少见。其早期多表现为无症状进行性下颌骨膨隆,影像学呈颌骨内颊舌向膨隆的骨硬化环阴影。后期因该病可引起下唇麻木且影像学特点不典型,故极易误诊为下颌骨来源的恶性肿瘤。本文通过1例来源于下牙槽神经的神经鞘瘤的临床表现、病史回顾,结合文献复习讨论该病的临床特点、诊断及其预后情况。

关键词: 神经鞘瘤, 下颌骨, 下牙槽神经

Abstract:  Schwannomas are mostly derived from the Schwann cells of the peripheral nerve sheath. The tumors are solitary and enveloped, which grow slowly, have clear boundaries with the surrounding tissues and are often benign. Head and neck schwannomas mainly occur in cranial nerves and peripheral nerves, and head, face and tongue soft tissues are the most common; while sympathetic nerves are relatively rare, and neurilemmomas occurring in the mandible are more rare. The early manifestations of this disease are mainly asymptomatic progressive mandibular swelling, and the imaging findings are the shadow of the longitudinal axis of the jaw and the buccal-lingual ossification ring. In the later stage, it can cause numbness of lower lip and atypical imaging characteristics, so it is easy to be misdiagnosed as malignant tumors of mandibular origin. This article reviews the clinical manifestation and history of a schwannoma originating from inferior alveolar nerve, and discusses the clinical features, diagnosis and prognosis of the disease based on literature review.

Key words: Intraosseous schwannoma, Mandible, Inferior alveolar nerve

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