褪黑素在牙周炎诊治中的研究进展

摘要/Abstract

摘要： 褪黑素是一种色氨酸衍生的激素，由大脑松果体分泌。近年来，大量研究发现褪黑素可以促进牙周组织健康，其在牙周炎中的作用受到越来越多的关注。该文就褪黑素在唾液中的浓度与牙周炎的相关性、褪黑素改善牙周状态的机制以及褪黑素作为外源性化学因子应用在牙周骨组织工程中的研究进展进行综述，以期为牙周炎的诊断和治疗提供新思路。

关键词: 褪黑素, 骨, 牙周炎, 组织工程

Abstract: Melatonin is a tryptophan-derived hormone secreted by the pineal gland of the brain. In recent years，a large number of studies have found that melatonin can promote periodontal health，so its role in periodontitis has received more and more attention. This article reviews the correlation between melatonin concentration in saliva and periodontitis，the mechanisms of melatonin affecting periodontitis，and the progress in the application of melatonin as an exogenous chemical factor in periodontal bone tissue engineering， in hopes of providing new ideas for the diagnosis and treatment of periodontitis.

Key words: melatonin, bone, periodontitis, tissue engineering

杨世缘胡月周宇宁桂志鹏徐袁瑾. 褪黑素在牙周炎诊治中的研究进展[J]. 口腔医学, 2021, 41(3): 259-264.

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