口腔医学 ›› 2022, Vol. 42 ›› Issue (1): 92-96.doi: 10.13591/j.cnki.kqyx.2022.01.017

• 综述 • 上一篇    

牙周炎和前列腺疾病相关性研究现状

陈年杰1, 钟良军1,2   

  1. 1 杭州师范大学医学部口腔医学院,浙江杭州(310000);
    2 杭州师范大学附属医院口腔科,浙江杭州(310000)
  • 修回日期:2021-09-10 出版日期:2022-01-28 发布日期:2022-01-28
  • 通讯作者: 钟良军 Tel:(0571)88303551,E-mail:zymdxx@163.com
  • 基金资助:
    2020年杭州市卫生科技计划重大项目(Z2020046)

Research status of the relationship between periodontitis and prostate diseases

CHEN Nianjie, ZHONG Liangjun   

  1. College of Stomatology, School of Medicine, Hangzhou Normal University, Hangzhou 310000, China
  • Revised:2021-09-10 Online:2022-01-28 Published:2022-01-28

摘要: 牙周炎是常见的口腔炎症性疾病,有大量文献报告牙周炎与全身系统性疾病存在密切联系,如心血管疾病、2型糖尿病、早产低出生体重儿等。牙周炎与前列腺疾病有相似的风险因素,年龄、吸烟、肥胖和糖尿病以及炎症的刺激对疾病有显著影响。该文主要对牙周炎和前列腺疾病的相关性的研究情况,共同的影响因素,以及相关的生物学机制等进行综述。

关键词: 牙周炎, 良性前列腺增生, 前列腺癌, 前列腺特异性抗原, 雄激素剥夺疗法

Abstract: Periodontitis is a common oral inflammatory disease. An enormous amount of literature has reported that periodontitis is closely related to systemic diseases, such as cardiovascular disease, type 2 diabetes, premature low-birth weight infants and so on. Periodontitis and prostate diseases have similar risk factors. Age, smoking, obesity and diabetes, as well as inflammatory stimulation, have a significant impact on the disease. This article mainly reviews the research status of the relationship between periodontitis and prostate diseases, common influencing factors, and related biological mechanisms.

Key words: periodontitis, benign prostatic hyperplasia, prostate cancer, prostate-specific antigen, androgen deprivation therapy

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