口腔医学 ›› 2022, Vol. 42 ›› Issue (9): 842-845.doi: 10.13591/j.cnki.kqyx.2022.09.014

• 综述 • 上一篇    下一篇

纤调蛋白聚糖在口腔疾病中的研究进展

段沁颜1,2, 马吉远2, 程俊翔1,2, 洪锋1,2, 潘乐1,2, 胡亚军1,2   

  1. 1.湖北医药学院附属太和医院口腔医学中心,湖北十堰(442000);
    2.湖北医药学院口腔医学院口腔疾病研究所,湖北十堰(442000)
  • 修回日期:2022-02-21 发布日期:2022-09-20
  • 通讯作者: 胡亚军 E-mail:huyajun912@163.com
  • 基金资助:
    湖北省自然科学基金(2020CFB747);湖北医药学院研究生科技创新项目(YC2020036)

Research progress of fibromodulin in oral diseases

DUAN Qinyan, MA Jiyuan, CHENG Junxiang, HONG Feng, PAN Le, HU Yajun   

  1. Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China
  • Revised:2022-02-21 Published:2022-09-20

摘要: 纤调蛋白聚糖是一种富含亮氨酸的小分子蛋白聚糖,它在牙体组织的形成与成熟、牙槽骨的发育以及关节结构的组成中发挥着重要的生理功能,同时也参与牙周病、龋病、颞下颌关节病等病理状态的发生。该文就纤调蛋白聚糖在口腔疾病中的生理功能、病理作用以及潜在的临床应用等方面作一综述。

关键词: 纤调蛋白聚糖, 口腔疾病, 生理功能, 病理作用, 临床应用

Abstract: Fibromodulin is a small leucine-rich proteoglycan. It plays an important physiological role in the formation and maturation of dental tissue, the development of alveolar bone and the composition of joint structure. It also participates in the occurrence of periodontal disease, caries, temporomandibular joint disease and other pathological states. This article reviews the physiological function, pathological effect and potential clinical application of fibromodulin in oral diseases.

Key words: fibromodulin, oral disease, physiological function, pathological effect, clinical application

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