口腔医学 ›› 2023, Vol. 43 ›› Issue (11): 1034-1040.doi: 10.13591/j.cnki.kqyx.2023.11.013
修回日期:
2023-03-10
出版日期:
2023-11-28
发布日期:
2023-11-21
通讯作者:
赵 青 E-mail:基金资助:
WEI Xiaoyu,ZHANG Guanning,ZHAO Qing()
Revised:
2023-03-10
Online:
2023-11-28
Published:
2023-11-21
摘要:
由正畸治疗引发的牙根吸收通常使用“正畸诱导炎性牙根吸收(orthodontically induced inflammatory root resorption,OIIRR)”来描述,这是正畸治疗中常见且影响较为严重的并发症。正畸牙根吸收可发生在正畸治疗期间的任何时间,并导致牙齿预后不佳和疗效稳定性降低。因此,在临床诊疗中能预测患者牙根吸收的易感性,并规避可能引发牙根吸收的危险因素,使用合理的治疗手段,是正畸医生的必要技能。该文基于最新的临床和基础研究进展,将分类对正畸诱导炎性牙根吸收的风险因素进行综述,为正畸诊疗工作提供参考。
中图分类号:
魏晓渝, 张冠凝, 赵青. 正畸诱导炎性牙根吸收影响因素的研究进展[J]. 口腔医学, 2023, 43(11): 1034-1040.
WEI Xiaoyu, ZHANG Guanning, ZHAO Qing. Progress of the study on factors influencing orthodontically induced inflammatory root resorption[J]. Stomatology, 2023, 43(11): 1034-1040.
[1] |
Bayir F, Bolat Gumus E. External apical root resorption after orthodontic treatment:Incidence, severity and risk factors[J]. J Dent Res Dent Clin Dent Prospects, 2021, 15(2):100-105.
doi: 10.34172/joddd.2021.017 |
[2] |
Yamaguchi M, Fukasawa S. Is inflammation a friend or foe for orthodontic treatment?:Inflammation in orthodontically induced inflammatory root resorption and accelerating tooth movement[J]. Int J Mol Sci, 2021, 22(5):2388.
doi: 10.3390/ijms22052388 |
[3] |
Deng YQ, Sun YN, Xu TM. Evaluation of root resorption after comprehensive orthodontic treatment using cone beam computed tomography(CBCT):A meta-analysis[J]. BMC Oral Health, 2018, 18(1):116.
doi: 10.1186/s12903-018-0579-2 |
[4] |
Castro IO, Alencar AHG, Valladares-Neto J, et al. Apical root resorption due to orthodontic treatment detected by cone beam computed tomography[J]. Angle Orthod, 2013, 83(2):196-203.
doi: 10.2319/032112-240.1 pmid: 22812378 |
[5] |
Yassir YA, El-Angbawi AM, McIntyre GT, et al. A randomized clinical trial of the effectiveness of 0.018-inch and 0.022-inch slot orthodontic bracket systems:Part 1-duration of treatment[J]. Eur J Orthod, 2019, 41(2):133-142.
doi: 10.1093/ejo/cjy037 |
[6] |
Patel S, Saberi N, Pimental T, et al. Present status and future directions:Root resorption[J]. Int Endod J, 2022, 55(Suppl 4):892-921.
doi: 10.1111/iej.v55.S4 |
[7] |
Zain MNM, Yusof ZM, Basri KN, et al. Multivariate versus univariate spectrum analysis of dentine sialophosphoprotein(DSPP)for root resorption prediction:A clinical trial[J]. BMC Oral Health, 2022, 22(1):151.
doi: 10.1186/s12903-022-02178-2 |
[8] |
Silva HC, Lavado N, Canova F, et al. Influence of clinical factors on the protective or deleterious impact of genetic variants in orthodontically induced external root resorption:An observational study[J]. BMC Oral Health, 2022, 22(1):270.
doi: 10.1186/s12903-022-02306-y |
[9] | Krishnan V. Root resorption with orthodontic mechanics:Pertinent areas revisited[J]. Aust Dent J, 2017, 62(Suppl 1):71-77. |
[10] |
Haugland L, Kristensen KD, Lie SA, et al. The effect of biologic factors and adjunctive therapies on orthodontically induced inflammatory root resorption:A systematic review and meta-analysis[J]. Eur J Orthod, 2018, 40(3):326-336.
doi: 10.1093/ejo/cjy003 |
[11] |
Samandara A, Papageorgiou SN, Ioannidou-Marathiotou I, et al. Evaluation of orthodontically induced external root resorption following orthodontic treatment using cone beam computed tomography(CBCT):A systematic review and meta-analysis[J]. Eur J Orthod, 2019, 41(1):67-79.
doi: 10.1093/ejo/cjy027 |
[12] |
Khan AR, Fida M, Shaikh A. Evaluation of apical root resorption in endodontically treated and vital teeth in adult orthodontic subjects[J]. J Ayub Med Coll Abbottabad, 2018, 30(4):506-510.
pmid: 30632325 |
[13] |
Aman C, Azevedo B, Bednar E, et al. Apical root resorption during orthodontic treatment with clear aligners:A retrospective study using cone-beam computed tomography[J]. Am J Orthod Dentofac Orthop, 2018, 153(6):842-851.
doi: 10.1016/j.ajodo.2017.10.026 |
[14] |
Yassir YA, McIntyre GT, Bearn DR. Orthodontic treatment and root resorption:An overview of systematic reviews[J]. Eur J Orthod, 2021, 43(4):442-456.
doi: 10.1093/ejo/cjaa058 |
[15] |
Linkous ER, Trojan TM, Harris EF. External apical root resorption and vectors of orthodontic tooth movement[J]. Am J Orthod Dentofac Orthop, 2020, 158(5):700-709.
doi: 10.1016/j.ajodo.2019.10.017 |
[16] | 张海亮. 固定正畸后牙根吸收的部分影响因素分析[J]. 现代诊断与治疗, 2017, 28(18):3476-3478. |
[17] |
Pastro JDV, Nogueira ACA, Salvatore de Freitas KM, et al. Factors associated to apical root resorption after orthodontic treatment[J]. Open Dent J, 2018, 12:331-339.
doi: 10.2174/1874210601812010331 pmid: 29875885 |
[18] |
Nanekrungsan K, Patanaporn V, Janhom A, et al. External apical root resorption in maxillary incisors in orthodontic patients:Associated factors and radiographic evaluation[J]. Imaging Sci Dent, 2012, 42(3):147-154.
doi: 10.5624/isd.2012.42.3.147 pmid: 23071964 |
[19] |
Li TC, Zhou ZY, Wang H, et al. Effects of estrogen on root repair after orthodontically induced root resorption in ovariectomized rats[J]. Am J Orthod Dentofac Orthop, 2020, 158(2):247-263. e1.
doi: 10.1016/j.ajodo.2019.08.014 |
[20] |
Han J, Hwang S, Nguyen T, et al. Periodontal and root changes after orthodontic treatment in middle-aged adults are similar to those in young adults[J]. Am J Orthod Dentofac Orthop, 2019, 155(5):650-655. e2.
doi: 10.1016/j.ajodo.2018.05.027 |
[21] |
Iber-Díaz P, Senen-Carramolino R, Iglesias-Linares A, et al. GWAS of post-orthodontic aggressive external apical root resorption identified multiple putative loci at X-Y chromosomes[J]. J Pers Med, 2020, 10(4):169.
doi: 10.3390/jpm10040169 |
[22] |
Borges de Castilhos B, Machado de Souza C, Simas Netta Fontana MLS, et al. Association of clinical variables and polymorphisms in RANKL, RANK, and OPG genes with external apical root resorption[J]. Am J Orthod Dentofac Orthop, 2019, 155(4):529-542.
doi: 10.1016/j.ajodo.2018.05.016 |
[23] |
Deng LZ, Guo YW. Estrogen effects on orthodontic tooth movement and orthodontically-induced root resorption[J]. Arch Oral Biol, 2020, 118:104840.
doi: 10.1016/j.archoralbio.2020.104840 |
[24] |
Singh A, Gill G, Kaur H, et al. Role of osteopontin in bone remodeling and orthodontic tooth movement:A review[J]. Prog Orthod, 2018, 19(1):18.
doi: 10.1186/s40510-018-0216-2 |
[25] |
Albach FN, Wagner F, Hüser A, et al. Safety, pharmacokinetics and pharmacodynamics of single rising doses of BI 655064, an antagonistic anti-CD40 antibody in healthy subjects:A potential novel treatment for autoimmune diseases[J]. Eur J Clin Pharmacol, 2018, 74(2):161-169.
doi: 10.1007/s00228-017-2362-8 |
[26] |
Pinheiro LHM, Guimarães LS, Santos Antunes L, et al. Genetic variation involved in the risk to external apical root resorption in orthodontic patients:A systematic review[J]. Clin Oral Invest, 2021, 25(10):5613-5627.
doi: 10.1007/s00784-021-04074-5 pmid: 34392402 |
[27] |
Pandis N, Nasika M, Polychronopoulou A, et al. External apical root resorption in patients treated with conventional and self-ligating brackets[J]. Am J Orthod Dentofac Orthop, 2008, 134(5):646-651.
doi: 10.1016/j.ajodo.2007.01.032 |
[28] | Giordana Ariane Ribeiro Schwerz Antunes de Melo, Martelli K, et al. Influence of asthma on the degree of apical root resorption in orthodontically treated patients[J]. Iran J Ortho, 2018, 13(2):e9518. |
[29] |
Dos Santos CCO, Bellini-Pereira SA, Medina MCG, et al. Allergies/asthma and root resorption:A systematic review[J]. Prog Orthod, 2021, 22(1):8.
doi: 10.1186/s40510-021-00351-x |
[30] |
Vishwanath M, Chen PJ, Upadhyay M, et al. Orthodontic management of a patient with short root anomaly and impacted teeth[J]. Am J Orthod Dentofacial Orthop, 2019, 155(3):421-431.
doi: 10.1016/j.ajodo.2018.11.009 |
[31] |
Berry S, Javed F, Rossouw PE, et al. Influence of thyroxine supplementation on orthodontically induced tooth movement and/or inflammatory root resorption:A systematic review[J]. Orthod Craniofac Res, 2021, 24(2):206-213.
doi: 10.1111/ocr.v24.2 |
[32] |
Delitala AP, Scuteri A, Doria C. Thyroid hormone diseases and osteoporosis[J]. J Clin Med, 2020, 9(4):1034.
doi: 10.3390/jcm9041034 |
[33] |
Kaklamanos EG, Makrygiannakis MA, Athanasiou AE. Does medication administration affect the rate of orthodontic tooth movement and root resorption development in humans?A systematic review[J]. Eur J Orthod, 2020, 42(4):407-414.
doi: 10.1093/ejo/cjz063 |
[34] |
Spoerri A, Koletsi D, Eliades T. Intrinsic hormone-like molecules and external root resorption during orthodontic tooth movement. A systematic review and meta-analysis in preclinical in-vivo research[J]. Front Physiol, 2018, 9:303.
doi: 10.3389/fphys.2018.00303 |
[35] |
Janson G, Niederberger A, Garib DG, et al. Root resorption in class Ⅱ malocclusion treatment with Class Ⅱ elastics[J]. Am J Orthod Dentofac Orthop, 2016, 150(4):585-591.
doi: 10.1016/j.ajodo.2016.02.031 |
[36] |
Tieu LD, Saltaji H, Normando D, et al. Radiologically determined orthodontically induced external apical root resorption in incisors after non-surgical orthodontic treatment of Class Ⅱ division 1 malocclusion: A systematic review[J]. Prog Orthod, 2014, 15(1):48.
doi: 10.1186/s40510-014-0048-7 |
[37] |
Fernandes LQP, Figueiredo NC, Antonucci CCM, et al. Predisposing factors for external apical root resorption associated with orthodontic treatment[J]. Korean J Orthod, 2019, 49(5):310-318.
doi: 10.4041/kjod.2019.49.5.310 pmid: 31598487 |
[38] |
Currell SD, Liaw A, Blackmore Grant PD, et al. Orthodontic mechanotherapies and their influence on external root resorption:A systematic review[J]. Am J Orthod Dentofac Orthop, 2019, 155(3):313-329.
doi: 10.1016/j.ajodo.2018.10.015 |
[39] |
Motokawa M, Sasamoto T, Kaku M, et al. Association between root resorption incident to orthodontic treatment and treatment factors[J]. Eur J Orthod, 2012, 34(3):350-356.
doi: 10.1093/ejo/cjr018 |
[40] |
Bellini-Pereira SA, Almeida J, Aliaga-Del Castillo A, et al. Evaluation of root resorption following orthodontic intrusion:A systematic review and meta-analysis[J]. Eur J Orthod, 2021, 43(4):432-441.
doi: 10.1093/ejo/cjaa054 |
[41] |
Al-Falahi B, Hafez AM, Fouda M. Three-dimensional assessment of external apical root resorption after maxillary posterior teeth intrusion with miniscrews in anterior open bite patients[J]. Dental Press J Orthod, 2018, 23(6):56-63.
doi: S2176-94512018000600056 pmid: 30672986 |
[42] | 姜若萍, 张丁, 傅民魁. 固定正畸后牙根吸收的部分影响因素分析[J]. 中华口腔医学杂志, 2003, 38(6):455-457. |
[43] |
Linge BO, Linge L. Apical root resorption in upper anterior teeth[J]. Eur J Orthod, 1983, 5(3):173-183.
doi: 10.1093/ejo/5.3.173 |
[44] |
Li XY, Xu JC, Yin YY, et al. Association between root resorption and tooth development: A quantitative clinical study[J]. Am J Orthod Dentofac Orthop, 2020, 157(5):602-610.
doi: 10.1016/j.ajodo.2019.11.011 |
[45] |
Brezniak N, Wasserstein A. Root resorption after orthodontic treatment: Part 2. Literature review[J]. Am J Orthod Dentofacial Orthop, 1993, 103(2):138-146.
doi: 10.1016/S0889-5406(05)81763-9 |
[46] |
Marques LS, Ramos-Jorge ML, Rey AC, et al. Severe root resorption in orthodontic patients treated with the edgewise method: Prevalence and predictive factors[J]. Am J Orthod Dentofac Orthop, 2010, 137(3):384-388.
doi: 10.1016/j.ajodo.2008.04.024 |
[47] |
Weltman B, Vig KWL, Fields HW, et al. Root resorption associated with orthodontic tooth movement: A systematic review[J]. Am J Orthod Dentofac Orthop, 2010, 137(4):462-476.
doi: 10.1016/j.ajodo.2009.06.021 |
[48] |
Kaley J, Phillips C. Factors related to root resorption in edgewise practice[J]. Angle Orthod, 1991, 61(2):125-132.
doi: 10.1043/0003-3219(1991)061<0125:FRTRRI>2.0.CO;2 pmid: 2064070 |
[49] | Heboyan A, Avetisyan A, Karobari MI, et al. Tooth root resorption:A review[J]. Sci Prog, 2022, 105(3):368504221109217. |
[50] |
Walker SL, Tieu LD, Flores-Mir C. Radiographic comparison of the extent of orthodontically induced external apical root resorption in vital and root-filled teeth: A systematic review[J]. Eur J Orthod, 2013, 35(6):796-802.
doi: 10.1093/ejo/cjs101 |
[51] |
Alhadainy HA, Flores-Mir C, Abdel-Karim AH, et al. Orthodontic-induced external root resorption of endodontically treated teeth: A meta-analysis[J]. J Endod, 2019, 45(5):483-489.
doi: S0099-2399(19)30106-2 pmid: 30904319 |
[52] |
Villaman-Santacruz H, Torres-Rosas R, Acevedo-Mascarúa AE, et al. Root resorption factors associated with orthodontic treatment with fixed appliances:A systematic review and meta-analysis[J]. Dent Med Probl, 2022, 59(3):437-450.
doi: 10.17219/dmp/145369 |
[53] | de Freitas MR, Beltrão RTS, Janson G, et al. Evaluation of root resorption after open bite treatment with and without extractions[J]. Am J Orthod Dentofacial Orthop, 2007, 132(2):143.e15-143. e22. |
[54] | 王玉兰, 王铁军, 柳忠豪. 上颌切牙内收前后牙根及牙槽骨的变化[J]. 华西口腔医学杂志, 2018, 36(6):638-645. |
[55] | Ballard DJ, Jones AS, Petocz P, et al. Physical properties of root cementum:Part 11. Continuous vs intermittent controlled orthodontic forces on root resorption. A microcomputed-tomography study[J]. Am J Orthod Dentofac Orthop, 2009, 136(1):8.e1-8. e8. |
[56] |
Roscoe MG, Meira JBC, Cattaneo PM. Association of orthodontic force system and root resorption:A systematic review[J]. Am J Orthod Dentofac Orthop, 2015, 147(5):610-626.
doi: 10.1016/j.ajodo.2014.12.026 |
[57] |
Theodorou CI, Kuijpers-Jagtman AM, Bronkhorst EM, et al. Optimal force magnitude for bodily orthodontic tooth movement with fixed appliances:A systematic review[J]. Am J Orthod Dentofac Orthop, 2019, 156(5):582-592.
doi: 10.1016/j.ajodo.2019.05.011 |
[58] |
Levander E, Malmgren O. Evaluation of the risk of root resorption during orthodontic treatment:A study of upper incisors[J]. Eur J Orthod, 1988, 10(1):30-38.
doi: 10.1093/ejo/10.1.30 |
[59] | Maués CPR, do Nascimento RR, Vilella OD. Severe root resorption resulting from orthodontic treatment:Prevalence and risk factors[J]. Dental Press J Orthod, 2015, 20(1):52-58. |
[60] | Ageel BM, Siraj EA, Zawawi KH, et al. The prevalence of root resorption after orthodontic treatment in patients attending a university hospital dental clinic[J]. J Pharm Bioallied Sci, 2021, 13(Suppl 2):S965-S968. |
[61] |
Zhang XJ, Zhou H, Liao XL, et al. The influence of bracket torque on external apical root resorption in bimaxillary protrusion patients:A retrospective study[J]. BMC Oral Health, 2022, 22(1):7.
doi: 10.1186/s12903-022-02042-3 |
[62] |
Qin F, Zhou Y. The influence of bracket type on the external apical root resorption in class Ⅰ extraction patients—A retrospective study[J]. BMC Oral Health, 2019, 19(1):53.
doi: 10.1186/s12903-019-0743-3 |
[63] | Lopatiene K, Dumbravaite A. Risk factors of root resorption after orthodontic treatment[J]. Stomatologija, 2008, 10(3):89-95. |
[64] |
Gandhi V, Mehta S, Gauthier M, et al. Comparison of external apical root resorption with clear aligners and pre-adjusted edgewise appliances in non-extraction cases: A systematic review and meta-analysis[J]. Eur J Orthod, 2021, 43(1):15-24.
doi: 10.1093/ejo/cjaa013 |
[65] |
Fang XW, Qi R, Liu CF. Root resorption in orthodontic treatment with clear aligners: A systematic review and meta-analysis[J]. Orthod Craniofac Res, 2019, 22(4):259-269.
doi: 10.1111/ocr.12337 pmid: 31323701 |
[66] |
Barros SE, Janson G, Chiqueto K, et al. Root resorption of maxillary incisors retracted with and without skeletal anchorage[J]. Am J Orthod Dentofacial Orthop, 2017, 151(2):397-406.
doi: 10.1016/j.ajodo.2016.06.048 |
[67] |
St Martin JG, Javed F, Rossouw PE, et al. Influence of mini-screw implant-assisted intrusion on orthodontically induced inflammatory root resorption: A systematic review[J]. Eur Arch Paediatr Dent, 2021, 22(3):341-349.
doi: 10.1007/s40368-020-00588-w pmid: 33423207 |
[68] |
Chan E, Dalci O, Petocz P, et al. Physical properties of root cementum:Part 26. Effects of micro-osteoperforations on orthodontic root resorption: A microcomputed tomography study[J]. Am J Orthod Dentofac Orthop, 2018, 153(2):204-213.
doi: 10.1016/j.ajodo.2017.05.036 |
[69] |
Mehta S, Chen PJ, Kalajzic Z, et al. Acceleration of orthodontic tooth movement and root resorption with near and distant surgical insults: An in-vivo study on a rat model[J]. Int Orthod, 2021, 19(4):591-600.
doi: 10.1016/j.ortho.2021.10.002 |
[70] |
Thind SK, Chatterjee A, Arshad F, et al. A clinical comparative evaluation of periodontally accelerated osteogenic orthodontics with piezo and surgical bur: An interdisciplinary approach[J]. J Indian Soc Periodontol, 2018, 22(4):328-333.
doi: 10.4103/jisp.jisp_359_16 pmid: 30131625 |
[71] | 周威, 王林, 王亮, 等. 上颌阻生尖牙牵引治疗后邻近切牙牙根吸收情况的研究[J]. 口腔医学, 2022, 42(6): 525-528. |
[72] |
Arriola-Guillén LE, Ruíz-Mora GA, Rodríguez-Cárdenas YA, et al. Root resorption of maxillary incisors after traction of unilateral vs bilateral impacted canines with reinforced anchorage[J]. Am J Orthod Dentofac Orthop, 2018, 154(5):645-656.
doi: 10.1016/j.ajodo.2018.01.015 |
[73] |
Arriola-Guillén LE, Ruíz-Mora GA, Rodríguez-Cárdenas YA, et al. Influence of impacted maxillary canine orthodontic traction complexity on root resorption of incisors: A retrospective longitudinal study[J]. Am J Orthod Dentofac Orthop, 2019, 155(1):28-39.
doi: 10.1016/j.ajodo.2018.02.011 |
[74] |
Brusveen EMG, Brudvik P, Bøe OE, et al. Apical root resorption of incisors after orthodontic treatment of impacted maxillary canines: A radiographic study[J]. Am J Orthod Dentofac Orthop, 2012, 141(4):427-435.
doi: 10.1016/j.ajodo.2011.10.022 |
[1] | 马燕, 朱道俣, 张春霞, 陶李明. 成人骨性Ⅱ类错𬌗矫治前后上颌前牙牙根吸收的研究[J]. 口腔医学, 2023, 43(9): 814-818. |
[2] | 黄虹, 李媛, 景秋平, 石逸瑾, 阳胜军, 王东苗. 青少年正畸患者下颌第三磨牙萌出的影响因素研究[J]. 口腔医学, 2023, 43(8): 697-701. |
[3] | 杨振泽, 林军. 人工智能在正畸正颌联合治疗的应用及展望[J]. 口腔医学, 2023, 43(8): 747-751. |
[4] | 樊思羽, 薛逸文, 宋枭, 邓润智, 郝静. 上颌近中阻生尖牙伴发邻牙牙根吸收的临床特征研究[J]. 口腔医学, 2023, 43(7): 638-642. |
[5] | 张柯佳, 史学明, 胡丹艳, 钱心瑶, 刘璐玮, 曹丹, 严斌. 下前牙拥挤非拔牙患者正畸治疗后牙龈黑三角发生的影响因素研究[J]. 口腔医学, 2023, 43(6): 518-523. |
[6] | 蔡观慧,管兆兰,李根,王华,张卫兵. 正畸优先模式与手术优先模式对骨性Ⅲ类患者疗效的差异性研究[J]. 口腔医学, 2023, 43(4): 317-321. |
[7] | 肖沛,俞燕芳,杨海萍,何福明. Spee曲线在正畸中的研究进展[J]. 口腔医学, 2023, 43(4): 365-370. |
[8] | 范典, 刘浩, 袁长永, 王鹏来. 无托槽隐形矫治器力学性能的影响因素及研究进展[J]. 口腔医学, 2023, 43(3): 278-281. |
[9] | 管兆兰,钱雅婧,王威. 高频率使用多乐氟预防正畸患者牙脱矿的效果研究[J]. 口腔医学, 2023, 43(2): 141-144. |
[10] | 樊永杰,寇雅婷. 无托槽隐形矫治拔牙病例的后牙不同轴倾度对牙齿三维力学影响[J]. 口腔医学, 2023, 43(2): 104-109. |
[11] | 胡洁琼, 李青奕. 三维立体摄影测量技术与正畸[J]. 口腔医学, 2023, 43(11): 1047-1052. |
[12] | 林祥祥, 余飞, 宋艺蔚, 王莞, 弓国梁, 林新平. 内收上颌切牙时唇腭侧牙槽骨改建影响因素的研究进展[J]. 口腔医学, 2023, 43(11): 1053-1056. |
[13] | 许嘉宁, 金作林, 刘佳. 3D打印在口腔正畸领域的应用进展[J]. 口腔医学, 2023, 43(10): 925-929. |
[14] | 林国芬,许杨波,王思源,林梦娜,何福明. 种植失败原因分析[J]. 口腔医学, 2023, 43(1): 18-23. |
[15] | 项闫颜, 宋东升, 王绍泰, 王敏. 口腔治疗中前牙区美学的考量因素[J]. 口腔医学, 2022, 42(9): 838-841. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||