›› 2016, Vol. 36 ›› Issue (8): 686-688.

• Basic Research • Previous Articles     Next Articles

Observation of RANTES in various types of abnormal humour syndrome patients with oral lichen planus

  

  • Received:2015-12-14 Revised:2016-04-05 Online:2016-08-28 Published:2016-08-28

Abstract: Objective To observe the changes of regulated upon activation normal T cell expressed and secreted factor (RANTES) concentrations in various abnormal humour (Hilit) syndrome patients with oral lichen planus (OLP), and to explore the clinical significance in the classification of OLP by the humour theory of traditional Uighur medicine (TUM). Methods 76 cases of OLP patients were classified according to the classification of abnormal humour. Biopsies were collected from 76 patients with OLP lesions. Expressions of RANTES were determined by the streptavidin-peroxidase (SP) technique. Results There were 51 (67.11%) cases of abnormal Khan syndrome, 6 (7.89%) cases of abnormal Sapra syndrome, 15 (19.74%) cases of abnormal Balgham syndrome, and 4 (5.26%) cases of abnormal Sawda syndrome among the 76 cases of OLP patients. Expressions of RANTES in different abnormal humour syndrome patients with OLP were 52.63% in abnormal Khan syndrome, 7.89% in abnormal Sapra syndrome, and 14.47% in abnormal Balgham syndrome groups. Conclusion There might be possible correlation between abnormal Khan syndrom and OLP. RANTES may play a role in OLP process.

Key words: traditional Uighur medicine, oral lichen planus, abnormal humour, RANTES, traditional Uighur medicine, oral lichen planus, abnormal humour, RANTES

CLC Number: