Abstract: Objective To evaluate the efficacy of GTR with the implantation of autogenous dentin particles in treating periodontal osseous defect. Methods 42 patients without systemic disease, but with vertical bone absorption osseous defect who had been treated through initial therapy were selected. In the experimental group, 21 teeth of 21 patients, the autogenous dentin particles and collagen membrane were placed in the areas with alveolar bone defect, while in the control group, another 21 teeth of 21 patients,the Bio-Oss and collagen membrane were used. The patients were followed up at 3、6、12 months after operation. The response was evaluated with clinical parameters of PD, AL and X-ray examination. Results The following periodontal index including PD and AL significantly reduced in both groups post-operation(P<0.05), but the alveolar bone amount obviously increased in two groups. Conclusion The clinical effects of the treatment of periodontal bone defect by GTR with implantation of autogenous dentin particlesor Bio-Oss have no obvious differences.

Key words: periodontal osseous defect, autogenous dentin particular, GTR