黄芪在口腔医学中的应用研究进展

Abstract

Abstract: Astragalus membranaceus is one of the common traditional Chinese medicine and the medical community is gradually doing indepth research on its pharmacological effects. Astragalus membranaceus not only has the effects of regulating immunity and blood glucose, treating cardiovascular disease and urinary system disease, antitumor, antibacterial and antiviral, but also can inhibit the periodontal pathogens, treat diseases of the oral mucosa and promote periodontal tissue regeneration, and so on. This review describes the advances of the application of astragalus membranaceus in oral medicine.

Key words: astragalus membranaceus, oral disease, oral medicine

CLC Number:

R781.05

References

[1]吕萍.中药黄芪药理作用及应用研究[J].中国卫生产业, 2016, 13(34):193-
[2]范安静.中药黄芪的药理作用及临床应用研究[J].医学前沿, 2016, 6(28):339-340
[3] 高云峰，高娜.黄芪生理活性成分及其药理作用研究进展［J］.新农业，2017, 1：20-21.
[4] 王翔宇.黄芪现代药理及临床研究进展［J］.科技风，2017, 3：182.
[5]Li L，Hou X, Xu R, et al.Research review on the pharmacological effects of astragaloside IV[J].Fundam Clin Pharmacol, 2017, 31(1):17-36
[6] Jin M, Zhao K, Huang Q, et al.Structural features and biological activities of the polysaccharides from Astragalus membranaceus［J］.Int J Biol Macromol，2014, 64:257-266.
[7]滕腾, 孙鑫, 张冉, 等.黄芪多糖对高糖环境下 细胞活性影响的研究[J].牙体牙髓牙周病学杂志, 2015, 25(6):348-353
[8]Cheng X, Wei B, Sun L, et al.Astragaloside I Stimulates osteoblast differentiation through the Wntβcatenin signaling pathway[J].Phytother Res, 2016, 30(10):1680-1688
[9]张朝良, 孔祥丽, 陈思秀, 等.黄芪多糖对牙周膜细胞增殖与结构的形态学影响[J].华西口腔医学杂志, 2010, 28(5):556-559
[10]王相峰.黄芪多糖缓释纤维对成骨细胞增殖分化影响的研究［D］.长春：吉林大学，2015:1-38.
[11]施育才, 曾健, 王佩飞, 等.中药黄芪促进牙周组织再生的初步观察[J].口腔医学, 2010, 30(4):230-232
[12]刘国宁，陈斌，钱雯，等.香烟烟雾提取物对成纤维细胞家族的影响及黄芪甲苷干预作用[J].中国中西医结合皮肤性病学杂志, 2013, 12(2):69-74
[13]Zhao BJ，Zhang XF, Han W, et al.Wound healing effect of an Astragalus membranaceus polysaccharide and its mechanism[J].Mol Med Rep, 2017, 15(6):4077-4083
[14]熊乐琴，马昌杯，帅云飞，等.浅谈黄芪甲苷对人皮肤成纤维细胞增生和凋亡的影响[J].当代医药论丛, 2014, 12(8):132-133
[15]薄磊.黄芪多糖对口腔黏膜成纤维细胞生物学行为及实验性阿弗他溃疡模型大鼠免疫状态的影响［D］.兰州：兰州大学，2011:1-59.
[16]康欣，姜晓文，韩名书，等.黄芪提取物对 细胞增殖及胶原合成的影响[J].中国兽医杂志, 2014, 50(1):27-29
[17]胡继宏，路娟，赵翊，等.黄芪主要活性成分及其提取物对鼠骨髓间充质干细胞增殖作用的影响[J].时珍国医国药, 2016, 27(5):1070-1072
[18]刘海江，刘雪阳，李喧.黄芪甲苷对骨髓基质干细胞复合冻干骨支架体内异位成骨的影响[J].中国药物与临床, 2015, 15(12):1714-1716
[19]邹萍，胡翔，刘德伍.黄芪诱导人骨髓间充质干细胞向表皮样细胞的分化[J].中国组织工程研究与临床康复, 2009, 13(36):7099-7102
[20]张正亮.一种间充质干细胞培养基：中国，CN201610643723.2［P］.20161123.
[21]胡翔，邹萍，刘莉玲，等.黄芪对人皮肤表皮干细胞增殖活性的影响[J].中国组织工程研究与临床康复, 2009, 13(19):3689-3692
[22]杨建堂，袁晨，王凯.黄芪对大鼠牙龈β防御素 表达的影响[J].遵义医学院学报, 2015, 38(4):379-382
[23]张卓，李志刚.黄芪总苷对口腔癌细胞活力的影响及机制[J].中国实用医药, 2013, 8(30):249-250
[24]Huang WH，Liao WR, Sun RX, et al.Astragalus polysaccharide induces the apoptosis of human hepatocellular carcinoma cells by decreasing the expression of Notch1[J].Int J Mol Med, 2016, 38(2):551-557
[25]李炳红.黄芪对正畸牙移动过程中牙周膜组织OPG、RANKL的影响［D］.遵义：遵义医学院，2013:1-53.
[26]吴群，刘憨妮，孙旭东，等.黄芪对正加速度引起大鼠嚼肌细胞凋亡的影响[J].口腔颌面修复学杂志, 2015, 16(4):203-206
[27]王雪梅，薄磊，祁晶，等.黄芪多糖对大鼠口腔溃疡治疗作用研究[J].天然产物研究与开发, 2013, 25(3):321-324
[28]邵玲玲，邵丽黎，贾向东.黄芪注射液治疗复发性口腔溃疡的临床效果及机制探讨[J].中国中医药科技, 2015, 22(4):419-420
[29]哈斯塔娜.单味黄芪治疗肾病患者口腔溃疡例[J].内蒙古中医药, 2012, 31(4):39-
[30]贾英杰.论重剂黄芪在恶性肿瘤治疗中的运用[J].中国中医基础医学杂志, 2016, 22(4):540-541
[31]贾英杰.调强放射治疗联合黄芪多糖注射液治疗头颈部肿瘤的临床疗效[J].实用医学杂志, 2014, 30(10):1652-1654
[32]蔡凯, 胡联民, 谭长超，等.防治放射性口腔黏膜炎的中药方剂及其制作方法：中国，CN201410538875.7［P］.2015128.
[33]张沁.研究刺五加黄芪片和雷公藤片治疗口腔扁平苔藓前后的血小板聚集率和血液流变性变化及临床疗效[J].中国实用医药, 2016, 11(15):180-181
[34]鲍旭.黄芪注射液治疗脾虚湿盛型寻常型天疱疮临床效果观察[J].中医中药, 2013, 24(3):350-351
[35]曾健, 施育才, 张卫东, 等.中药黄芪辅助治疗牙周炎的效果观察[J].口腔医学, 2011, 31(7):401-403

Research progress of the application of astragalus membranaceus in oral medicine

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