›› 2019, Vol. 39 ›› Issue (5): 468-471.

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The association between Matrix metalloproteinase 13 and common oral disease

  

  • Received:2018-06-21 Revised:2018-08-12 Online:2019-05-28 Published:2019-05-21

Abstract: Abstract:Matrix metalloproteinase-13 (MMP-13),is an important member of the matrix metalloproteinase family and is secreted by inactive zymogen.It has been involved in the normal physiological and pathological processes of the human body and can degrade the extracellular matrix alone or in combination with other Matrix metalloproteinases, which are expressed in a variety of cells in the body. This article intends to summarize the close relationship between abnormal changes of MMP-13 expression and common oral diseases such as periodontitis, apical periodontitis and oral squamous cell carcinoma.

Key words: MMP13, extracellular matrix, oral disease

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