›› 2019, Vol. 39 ›› Issue (4): 354-359.

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The chitosan drug delivery system and its application in bone tissue engineering

Yang LIU1, 2   

  1. 1. The Affiliated Stomatology Hospital of Tongji University
    2.
  • Received:2018-07-26 Revised:2018-08-31 Online:2019-04-28 Published:2020-01-13

Abstract: Chitin is the second most abundant natural resource after cellulose. Chitosan is the product of of the deacylation reaction of chitin. It is the unique cationic polysaccharide in the nature which excellent properties of biocompatibility and biodegradability. The drug delivery systems based on chitosan are proved to be in favor of improving the drug bioavailability , changing its delivery mode and controlling drug release. This review summarizes the research progress of chitosan-based drug delivery systems and its applications in bone tissue engineering.

Key words: chitosan, drug delivery, bone tissue engineering