Abstract: Objective To summarize clinical outcomes of immediate loading and nonimmediate loading, judging that whether the outcome of immediate loading implants can be expected, and whether it can satisfy clinical demand and potential influencing factors, giving suggestions to further clinical trials. Methods Our study searched foreign database for relevant articles up to December 2018, and collected clinical parameters of immediate and nonimmediate loading implants including marginal bone loss, marginal bone loss change, implant stability quotient and survival rate of implants, established database to perform Metaanalysis. Results Finally, 32 studies were included in the analysis. As for marginal bone loss, marginal bone loss change, implant stability quotient and survival rate of implants, there was no significant difference between clinical outcomes of immediate loading and nonimmediate loading. Conclusion It is shown that there is no significant difference between immediate loading and nonimmediate loading for implant restoration on patients without systematic diseases, and the outcome of immediate loading implant is expectable.

Key words: oral implantology, immediate loading, marginal bone loss, survival rate of implants, Meta analysis