›› 2021, Vol. 41 ›› Issue (9): 843-846.

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Research progress of SOX2 in head and neck squamous cell carcinoma

  

  • Received:2020-11-24 Revised:2021-01-13 Online:2021-09-28 Published:2021-09-23

Abstract: SOX2 gene plays an important role in the pluripotency and growth of embryonic stem cells, and is also one of the common tumor stem cell markers. Recent studies have confirmed that tumor stem cells are closely related to the occurrence, development and metastasis of cancer. This article reviews the mechanism and role of SOX2 gene in early diagnosis, proliferation, metastasis, prognosis and treatment of head and neck squamous cell carcinoma.

Key words: SOX2, head and neck squamous cell carcinoma, cancer stem cell

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