β-抑制蛋白2调节炎症性疾病作用机制的研究进展

doi:10.13591/j.cnki.kqyx.2022.06.011

口腔医学 ›› 2022, Vol. 42 ›› Issue (6): 540-544.doi: 10.13591/j.cnki.kqyx.2022.06.011

β-抑制蛋白2调节炎症性疾病作用机制的研究进展

冯梅婷, 罗礼君

同济大学附属口腔医院牙周病科·上海牙组织修复与再生工程技术研究中心,上海(200072)

修回日期:2021-12-07 出版日期:2022-06-28 发布日期:2022-07-21
通讯作者: 罗礼君 E-mail:juneluo@yeah.net
基金资助:
国家自然科学基金面上项目(82071123)

Progress of research on mechanism of β-arrestin 2 regulating inflammatory disease

FENG Meiting, LUO Lijun

Department of Periodontics, School of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072,China

Revised:2021-12-07 Online:2022-06-28 Published:2022-07-21

摘要/Abstract

摘要： β-抑制蛋白2是抑制蛋白家族成员,主要通过G蛋白偶联受体(G protein-coupled receptor, GPCR)信号通路传导以及参与多种炎症信号通路在炎症性疾病中发挥重要作用。本文回顾了β-抑制蛋白2的结构功能,并就β-抑制蛋白2在炎症性疾病中的作用机制进行综述。

关键词: β-抑制蛋白2, 炎症性疾病, G蛋白偶联受体

Abstract: β-arrestin 2 belongs to the inhibitory protein family which plays a pivotal role in inflammatory diseases, and it involves in inflammatory diseases through the G protein-coupled receptor(GPCR) signal transduction pathway and its participation in various signaling pathways. In this paper we review the function of β-arrestin 2 and summarize the mechanism of β-arrestin 2 in inflammatory diseases.

Key words: β-arrestin 2, inflammatory disease, G protein-coupled receptor

中图分类号:

R363

冯梅婷, 罗礼君. β-抑制蛋白2调节炎症性疾病作用机制的研究进展[J]. 口腔医学, 2022, 42(6): 540-544.

FENG Meiting, LUO Lijun. Progress of research on mechanism of β-arrestin 2 regulating inflammatory disease[J]. Stomatology, 2022, 42(6): 540-544.

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β-抑制蛋白2调节炎症性疾病作用机制的研究进展

Progress of research on mechanism of β-arrestin 2 regulating inflammatory disease

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