Wnt/β-catenin通路与NF-κB通路的交叉调控对间充质干细胞分化的影响

doi:10.13591/j.cnki.kqyx.2023.02.014

摘要/Abstract

摘要：

Wnt/β-catenin信号通路与NF-κB信号通路都是高度保守的通路,调节多种生物学过程,二者之间的交叉影响已在多个生物和医学研究领域引起重视。该文将就Wnt/β-catenin信号通路与NF-κB信号通路的相互作用及对间充质干细胞多向分化的影响进行综述。

关键词: Wnt/β-catenin, NF-κB, 间充质干细胞, 组织再生

Abstract:

Both Wnt/β-catenin signaling pathway and NF-κB signaling pathway are highly conservative pathways that regulate a variety of biological processes, and their cross-regulation have attracted attention in many biological and medical research fields. In this review, we summarize the cross-regulation between Wnt/β-catenin signaling pathway and NF-κB signaling pathway and discuss their involvement in the multi-directional differentiation of mesenchymal stem cells.

Key words: Wnt/β-catenin, NF-κB, mesenchymal stem cell, tissue regeneration

中图分类号:

R349.64

孙佳瑶,宗斌,谢雨桐,徐全臣. Wnt/β-catenin通路与NF-κB通路的交叉调控对间充质干细胞分化的影响[J]. 口腔医学, 2023, 43(2): 170-175.

SUN Jiayao,ZONG Bin,XIE Yutong,XU Quanchen. Cross-regulation of Wnt/β-catenin and NF-κB signaling pathway and their involvement in the differentiation of mesenchymal stem cells[J]. Stomatology, 2023, 43(2): 170-175.

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