渗透树脂对早期釉质龋的防治效果观察

doi:10.13591/j.cnki.kqyx.2023.10.002

摘要/Abstract

摘要：

目的探讨渗透树脂防治早期龋的效果,为临床选择安全有效、简单易行的早期釉质龋防治方法提供实验依据。方法实验收集10~25岁患者由于正畸拔除的上下前磨牙110颗,采用酸凝胶法形成人工釉质龋后,运用原子吸收分光光度计检测酸性溶液中的Ca²⁺含量,比较渗透树脂、氟保护漆以及氟化钠的应用对脱矿牙釉质表面抗酸性的影响,采用扫描电镜观察釉质表面及纵剖面的超微结构,评价渗透树脂封闭釉质脱矿区的情况,从而深入探讨渗透树脂的抗酸性能及防龋效果。结果 Ca²⁺浓度测量结果显示,渗透树脂组、氟保护漆组及氟化钠组的Ca²⁺溶出量分别为(6.432±1.867)、(31.208±7.784)、(41.176±3.512)μg/mL,渗透树脂组明显低于氟保护漆组和氟化钠组,差异有统计学意义(P<0.01)。SEM观察结果显示:渗透树脂组可见釉质表面有完整、相对平滑的材料覆盖,树脂在釉质表层形成一薄层树脂膜,并能较好地渗入釉质脱矿产生的孔隙中呈密集的网筛状,氟保护漆及氟化钠组在釉质表层形成的漆膜,似碎玻璃状晶体结构,空隙直径明显大于渗透树脂组。结论渗透树脂能有效抑制釉质的脱矿,增强人牙釉质表面的抗酸性能,明显优于氟保护漆及氟化钠。

关键词: 龋病, 釉质龋, 氟化钠, 氟保护漆, 渗透树脂, 抗酸性

Abstract:

Objective To evaluate the utility of Icon in preventing early enamel caries and provide a theoretical and laboratory research basis to cure early enamel caries in a safe, effective, easy and feasible way. Methods In the present study, 110 premolars of patients aged 10-25 who underwent orthodontic treatment were included. The artificial caries samples were established with an acid gel. The atomic absorption spectrophotometer was used to detect concentration of Ca²⁺in an acid solution and the anti-acid effect of enamel surface with Icon, fluoride protector and sodium fluoride was evaluated. The scanning electron microscope was used to observe ultrastructure of enamel surfaces and the longitudinal profile and then the blocking effect of demineralization zone with Icon was evaluated. Results The measurement results of Ca²⁺ concentration showed that the Ca²⁺ release levels in the Icon group, fluoride protector group, and sodium fluoride group were (6.432±1.867), (31.208±7.784), and (41.176±3.512)μg/mL, respectively. The Ca²⁺release in the resin infiltration group was significantly lower than that in the fluoride protector group and sodium fluoride group, with statistically significant difference (P<0.01). SEM observations revealed that the enamel surface in the Icon group exhibited a complete and relatively smooth material coverage. Icon formed a thin resin film on the enamel surface and penetrated well into the porous demineralized areas, forming a dense mesh-like network. Fluoride protector and sodium fluoride groups exhibited a fractured glass-like crystalline structure on the enamel surface, with significantly larger void diameters compared to the Icon group. Conclusion Icon can inhibit enamel demineralization effectively and enhance the acid resistance of enamel surface. It is better than fluoride protector and sodium fluoride.

Key words: dental caries, enamel caries, sodium fluoride, fluoride protector, infiltrated resin, acid resistance

中图分类号:

R788.1

刘欣, 黄银珠, 金成日. 渗透树脂对早期釉质龋的防治效果观察[J]. 口腔医学, 2023, 43(10): 872-877.

LIU Xin, HUANG Yinzhu, JIN Chengri. Observation of Icon on early enamel caries prevention and treatment[J]. Stomatology, 2023, 43(10): 872-877.

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分组	n	Ca²⁺/(μg/mL)
渗透树脂组(A组)	20	6.432±1.867^abcd
氟保护漆组(B组)	20	31.208±7.784^abce
氟化钠组(C组)	20	41.176±3.512^abde
阳性对照组(D组)	20	77.616±10.789^bcde
阴性对照组(E组)	20	0.109±0.535^acde