口腔医学 ›› 2025, Vol. 45 ›› Issue (12): 923-926.doi: 10.13591/j.cnki.kqyx.2025.12.008

• 基础与临床研究 • 上一篇    下一篇

氧化亚氮镇静在儿童口腔治疗中的临床研究

俞少玲, 李姮, 邢向辉()   

  1. 南京大学医学院附属口腔医院,南京市口腔医院,南京大学口腔医学研究所儿童口腔科,江苏南京(210008
  • 收稿日期:2025-05-03 出版日期:2025-12-28 发布日期:2025-12-16
  • 通讯作者: 邢向辉 E-mail:dr.xing@qq.com
  • 基金资助:
    2020年江苏特聘医学专家项目(2021-39)

Clinical study on nitrous oxide sedation in children oral treatment

YU Shaoling, LI Heng, XING Xianghui()   

  1. Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Department of Pediatric Stomatology, Institute of Stomatology, Nanjing University, Nanjing 210008, China
  • Received:2025-05-03 Online:2025-12-28 Published:2025-12-16
  • Contact: XING Xianghui E-mail:dr.xing@qq.com

摘要:

目的 分析氧化亚氮/氧气(N2O/O2)吸入镇静在牙科畏惧症患儿乳牙根管治疗中的疗效,探索精细化给药的可行性。 方法 随机选取在我院儿童口腔科就诊需进行乳牙根管治疗的牙科畏惧症患儿37例,术前采用Frankl行为测试量表对患儿牙科畏惧症程度进行评估,使用N2O/O2镇静辅助口腔治疗。术后使用Houpt行为量表评价患儿对治疗的依从性,并进行术后评估。 结果 轻、中度畏惧症组患儿25例,均成功完成口腔治疗,成功率100%。重度畏惧症组患儿12例,成功完成治疗10例,成功率83.3%。两组差异无统计学意义(P=0.099)。轻、中度牙科畏惧症组患儿术中N2O维持浓度及最高浓度较重度畏惧症组显著降低(P<0.05)。 结论 轻、中度牙科畏惧症患儿使用N2O/O2吸入镇静后口腔治疗效果较好。术前评估患儿焦虑状态有助于治疗中N2O浓度的选择,达到精细化给药的目的。

关键词: 儿童牙科畏惧症, N2O/O2, 吸入镇静, 精细化给药, 乳牙根管治疗

Abstract:

Objective To analyze the efficacy of nitrous oxide/oxygen (N2O/O2) inhalation sedation in the root canal treatment of deciduous teeth in children with dental phobia, and explore the feasibility of refined drug delivery. Methods Thirty-seven patients who needed root canal treatment in pediatric dentistry were randomly selected, and the degree of dental fear was evaluated using the Frankl Behavior Scale before surgery. N2O/O2 sedation was used to assist in oral treatment. The compliance of the child with treatment was evaluated using the Houpt Behavior Scale after surgery and postoperative assessment was conducted. Results Twenty-five children in the mild to moderate fear group successfully completed oral treatment, with a success rate of 100%. There were 12 children in the severe fear group, and 10 of them successfully completed treatment, with a success rate of 83.3%. The difference between the two groups was statistically significant (P=0.099). The maintenance concentration and maximum concentration of N2O during surgery were significantly lower in the mild to moderate dental phobia group compared to the severe phobia group (P<0.05). Conclusion The oral treatment effect of N2O/O2 inhalation sedation is better in children with mild to moderate dental phobia. Preoperative assessment of anxiety status in pediatric patients can help to select N2O concentration during treatment, achieving the goal of precise administration.

Key words: dental anxiety in children, N2O/O2, inhalation sedation, precise drug administration, root canal treatment for deciduous teeth

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