SPECT/CT同机融合显像在口腔鳞癌前哨淋巴结定位中的应用

›› 2014, Vol. 34 ›› Issue (11): 828-831.

SPECT/CT同机融合显像在口腔鳞癌前哨淋巴结定位中的应用

藕小平¹,吴渺夷¹,张胜²,吕冲¹,俞韬¹

1. 宁波市北仑区人民医院
2. 东莞市人民医院

收稿日期:2014-03-10 修回日期:2014-04-08 出版日期:2014-11-28 发布日期:2014-12-03
通讯作者: 藕小平 E-mail:oxping@126.com
基金资助:
浙江省卫生厅项目

The application of SPECT/CT Co-registration Fusion Scintigraphy in Sentinel Lymph Node Localization in cN0 Oral Squamous Cell Carcinoma

Received:2014-03-10 Revised:2014-04-08 Online:2014-11-28 Published:2014-12-03
Contact: Xiao-Ping OU E-mail:oxping@126.com

摘要/Abstract

摘要： 目的　探索一种准确、实用的口腔鳞癌前哨淋巴结定位方法。方法　术前运用SPECT/CT同机融合显像技术对30例cN0期口腔鳞癌患者的SLN进行定位，术中对定位的SLN活检，术后比较SLN与颈淋巴清扫的病理结果。结果　全组病例中，SPECT/CT同机融合图像对SLN定位的准确度为100%， 8例患者的前哨淋巴结和颈清扫淋巴结病理结果证实有癌转移，前哨淋巴结活检对颈部淋巴结转移状况评价的敏感度、特异度和准确度均为100%。结论　SPECT/CT同机融合显像技术可以在术前准确定位前哨淋巴结，客观评价cN0期口腔鳞癌患者颈部淋巴结的真实状况。

关键词: 口腔癌, 鳞状细胞癌, 前哨淋巴结, 肿瘤转移

Abstract: Objective　To explore an accurate and available method in sentinel lymph node localization in cN0 oral squamous cell carcinoma. Methods　Preoperative sentinel lymph node localization by SPECT/CT Co-registration Fusion Scintigraphy and intraoperative sentinel lymph node biopsy were performed to evaluate the cervical lymph node status in 30 cases of cN0 oral squamous cell carcinoma and the pathological results of SLN and neck dissection were compared after the operation. Results　Among all the 30 cases, the accuracy rating of sentinel lymph node localization by SPECT/CT Co-registration Fusion Scintigraphy was 100%. Sentinel lymph nodes were found with metastasis in 8 cases. No non-sentinel lymph node was found with metastasis while sentinel lymph nodes were pathologically negative. The sensitivity, specificity and accuracy of evaluation of neck lymph node metastasis were 100%. Conclusion　Preoperative SPECT/CT Co-registration Fusion Scintigraphy can be used to locate sentinel lymph node and accurately evaluate the statue of cervical lymph node metastasis in cN0 oral squamous cell carcinoma.

Key words: Oral cancer, squamous cell carcinoma, Sentinel lymph node, metastasis

中图分类号:

R739.86

藕小平吴渺夷张胜吕冲俞韬. SPECT/CT同机融合显像在口腔鳞癌前哨淋巴结定位中的应用[J]. 口腔医学, 2014, 34(11): 828-831.

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