›› 2014, Vol. 34 ›› Issue (2): 91-94.

• 基础与临床研究 • 上一篇    下一篇

关节上腔对比关节下腔注射透明质酸治疗颞下颌关节病效果的Meta分析

方建红1,徐俊峰2,李森强2,朱国光2   

  1. 1. 浙江省立同德医院
    2. 浙江省立同德医院口腔科
  • 收稿日期:2013-05-06 修回日期:2013-06-18 出版日期:2014-02-28 发布日期:2014-03-05
  • 通讯作者: 方建红 E-mail:da12da12@163.com
  • 基金资助:
    浙江省中医药科学研究基金计划

Meta analysis of the effect of superior and inferior temporomandibular joint space injection of sodium Hyaluronate for temporomandibular arthrosis treatmentfor temporomandibular arthrosis treatment

  • Received:2013-05-06 Revised:2013-06-18 Online:2014-02-28 Published:2014-03-05

摘要: 目的 系统评价关节上腔对比关节下腔注射透明质酸治疗颞下颌关节病的疗效。 方法 计算机检索Embase、Cochrane Library、pubmed、万方、维普等数据库,检索时间从1995年至2013年5月30日,查找有关关节上腔和关节下腔注射透明质酸治疗颞下颌关节病的随机对照试验(RCT),按纳入排除标准选择文献、提取资料和评价质量后,采用REVMAN软件进行Meta分析。 结果 共纳入4个RCT,共514例患者。Meta分析结果显示,与关节上腔注射相比,关节下腔注射透明质酸更能降低患者的关节疼痛。 结论 与关节上腔注射相比,关节下腔注射透明质酸的效果更好,在临床上具有一定的应用价值。

关键词: 关节腔, 透明质酸, 颞下颌关节病, Meta分析, temporomandibular joint space, sodium Hyaluronate, temporomandibular arthrosis, Meta-analysis

Abstract: Objective To evaluate the effectiveness of superior and inferior temporomandibular joint space injection of sodium Hyaluronate for temporomandibular disorders treatment. Methods Searching various databases such as Embase,Cochrane Library,Pubmed,Wanfang and Weipu etc.for papers on superior and inferior joint compartment injection of sodium Hyaluronate for temporomandibular arthrosis treatment RCT,which were published from 1995 to Dec.16th,2011.After paper selection in accordance with inclusion and exclusion criteria,data extraction and the quality evaluation,REVMAN software was used for Meta analysis. Results A total of 4 RCTs involving 514 patients were included.The Meta analysis showed that there was a significant reduction of TMJ pain in the inferior joint injection group compared with the superior joint injection group. Conclusions This study showed that inferior joint space injection of sodium hyaluronate is an effective way for temporomandibular arthrosis treatment,thus it has certain application value.

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