骨保护素在牙根吸收中保护作用的研究进展

摘要/Abstract

摘要： ［摘要］牙根吸收是一种生理性或病理性牙本质、牙骨质缺损的临床现象，为口腔科常见病。目前对于牙根吸收尚无有效预防手段和治疗方法。有关牙根吸收机制的研究，近几年发现骨保护素（osteoprotegerin,OPG）在此过程中起重要作用，本文就近几年OPG的结构、表达及功能，OPG/核因子kB受体活化因子配体（ligand of receptor activator of NF-κB,RANKL）/核因子kB受体活化因子（receptor activator NF-κB,RANK）系统，OPG在牙根周围相关组织中的保护作用作一综述。

关键词: 牙根吸收, 骨保护素, 保护作用

Abstract: Abstract: Root resorption is a physiological or pathological phenomenon of dentin and cementum defects. It is common in oral diseases. Root resorption often causes reduction of the tooth crown-root ratio and decreases tooth stability, which leads to the looseness or even falling off of teeth, thus seriously affecting the oral health and appearance. So far, there hasn’t been any effective way to prevent or cure root resorption. In recent years, it has been found that osteoprotegerin (OPG) plays an important role in root resorption. This article reviewed the structure, expression and function of OPG, OPG/RANKL/RANK system and the protective effects of OPG on related tissues around root.

Key words: root resorption, osteoprotegerin, protective effects

中图分类号:

R781.3

刘艺张旗. 骨保护素在牙根吸收中保护作用的研究进展[J]. , 2015, 35(11): 979-982.

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