纳米二氧化钛对正畸粘接剂抗菌性与拉伸粘接强度的影响

›› 2016, Vol. 36 ›› Issue (7): 591-594.

纳米二氧化钛对正畸粘接剂抗菌性与拉伸粘接强度的影响

李振霞¹,薛晶¹,陈婷婷²,张强³

1. 口腔疾病研究国家重点实验室，四川大学；四川大学华西口腔医学院
2. 深圳市妇幼保健院
3. 南方医科大学附属深圳市妇幼保健院口腔病防治中心

收稿日期:2016-01-28 修回日期:2016-03-07 出版日期:2016-07-28 发布日期:2016-07-19
通讯作者: 张强 E-mail:13500052738@163.com
基金资助:
正畸托槽对口腔微生物基因型的影响

Effect of TiO2 nanoparticles on the antibacterial effects and tensile bonding strength of orthodontic adhesive

Received:2016-01-28 Revised:2016-03-07 Online:2016-07-28 Published:2016-07-19

摘要/Abstract

摘要： 目的研究纳米级二氧化钛对正畸托槽粘接剂抗菌效果及拉伸粘接强度的影响。方法在光固化托槽粘接剂（Grengloo）中加入质量分数1%、2%、3%纳米级二氧化钛。空白对照组不加入二氧化钛。将托槽粘接于离体前磨牙上，测量拉伸粘接强度与粘接剂残留量。粘接剂制成树脂圆片与菌悬液共培养48 h后，进行细菌活性与代谢测定。结果 4组粘接剂的拉伸粘接强度和粘接剂残留指数无显著差异。2%、3%组的pH值明显增加、乳酸产生量明显减少，但两组间无明显差别。加入纳米二氧化钛的三组菌落计数均明显减少，但3组间无明显差别。结论 2%纳米二氧化钛对Grengloo托槽粘接剂拉伸粘接强度无明显影响，同时提高其抗菌性。

关键词: 纳米二氧化钛, 正畸粘接剂, 抗菌性, 拉伸粘接强度

Abstract: Objective To evaluate the effect of titanium dioxide (TiO2) nanoparticles on tensile bonding strength (TBS) and antibacterial properties of an orthodontic adhesive. Methods Light cure orthodontic adhesive (Grengloo) was blended with TiO2 nanoparticles by 1%, 2%, 3% (mass fraction). The control was not blended with TiO2. Brackets were bonded to extracted premolars by these new adhesives. TBS of four groups was determined, and the adhesive remnant index (ARI) scores were assessed. A total of 20 composite discs specimen were prepared, and incubated with bacterial suspension for 48 hours and tested for antibacterial properties. Results No significant difference was found among TBS and ARI of the four groups. PH values of group 2% and 3% were significantly increased and lactate production was significantly reduced compared with the control group, but no significant difference was found between these two groups. The colony unit counts of the three groups containing TiO2 were significantly reduced, but no significant difference among these three groups was observed. Conclusion Adding 2%TiO2 to Grengloo enhances its antibacterial effects without increasing the tensile bonding strength.

Key words: TiO2 nanoparticles, orthodontic adhesive, antibacterial, tensile bonding strength

中图分类号:

R783.5

李振霞薛晶陈婷婷张强. 纳米二氧化钛对正畸粘接剂抗菌性与拉伸粘接强度的影响[J]. , 2016, 36(7): 591-594.

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