变形链球菌葡聚糖结合蛋白研究进展

摘要/Abstract

摘要： 葡聚糖结合蛋白是变形链球菌致龋的重要毒力因子。与变形链球菌的粘附、聚集、细胞壁生理功能、酶活性和形成生物膜并维持其结构稳定起重要作用。该文就变形链球菌4种葡聚糖结合蛋白研究现状，葡聚糖结合蛋白与生物膜、防龋疫苗的关系及当前存在的问题作一综述。

关键词: 葡聚糖结合蛋白, 葡聚糖, 生物膜, 防龋疫苗

Abstract: Glucanbinding proteins (Gbps) are important virulence factors in the cariogenicity of streptococcus mutans (S.mutans). Glucanbinding proteins play an important role in the adhesion and aggregation of S.mutans, and are involved in physiological function of cell wall and enzyme activity; they also have an effect on the biofilm formation and maintain the stability of biofilm architecture. The article reviewed current status of four glucanbinding proteins, their relationships with biofilm and anticaries vaccine, and existing problems.

Key words: glucan-binding proteins, glucan, biofilm, anti-caries vaccine.

中图分类号:

R780.2

徐帅妹魏信汉崔力. 变形链球菌葡聚糖结合蛋白研究进展 [J]. , 2016, 36(7): 662-665.

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