骨形成蛋白-2与其他生长因子联合应用对骨再生的影响

摘要/Abstract

摘要： 随着组织工程的发展，越来越多的生长因子被应用到组织工程中参与骨组织的改建与修复再生，骨形成蛋白-2（bone morphogenetic protein 2, BMP-2）是最为常用的促进成骨分化及骨组织再生的生长因子，并且BMP-2与其他因子的联合应用成为目前研究的热点，本文主要阐述BMP-2与其他因子联合应用时所产生的促成骨效应及其作用机制。

关键词: 组织工程, 骨再生, 骨形成蛋白-2, 碱性成纤维细胞生长因子, 联合应用

Abstract: 　With the development of tissue engineering, more and more growth factors are applied to the reconstruction and regeneration of bone tissue in tissue engineering. Bone morphogenetic protein 2 (BMP-2) is the most common growth factor which is used to promote osteogenic differentiation and bone regeneration. Currently, the combined application of BMP-2 with other factors is becoming a research hotspot. This paper mainly introduces the effect and mechanism of combined application of BMP-2 with other factors.

Key words: Tissue engineering, bone regeneration, bone morphogenetic protein 2, basic fibroblast growth factor, combined application

中图分类号:

R782

商玲玲葛少华. 骨形成蛋白-2与其他生长因子联合应用对骨再生的影响[J]. , 2017, 37(11): 1029-1033.

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