低频超声对牙菌斑生物膜促渗作用的研究进展

›› 2019, Vol. 39 ›› Issue (2): 179-182.

低频超声对牙菌斑生物膜促渗作用的研究进展

马巍,王涛

哈尔滨医科大学附属第四医院

收稿日期:2018-05-11 修回日期:2018-06-05 出版日期:2019-02-28 发布日期:2019-03-05
通讯作者: 王涛 E-mail:wangtaomawei@sohu.com
基金资助:
甲苯胺蓝介导低频超声促渗对菌斑生物膜信号系统的影响;甲苯胺蓝介导的低频超声在牙菌斑生物膜中促渗机制的研究;HMME介导的低频超声促渗作用对菌斑生物膜AI-2信号系统的影响;黑龙江省大学生创新创业训练计划项目;黑龙江省大学生创新创业训练计划项目

Advances in research on permeability of dental plaque biofilm by low frequency ultrasound

Received:2018-05-11 Revised:2018-06-05 Online:2019-02-28 Published:2019-03-05

摘要/Abstract

摘要： 牙菌斑生物膜是一种细菌性生物膜，为基质包裹的互相粘附，或粘附于牙面、牙间或修复体表面的软而未矿化的细菌性群体，不能被水冲去或漱掉。它是一个具有结构、形态和代谢活动的独立微生态环境，其耐药性是浮游生物的许多倍。研究人员发现，低频率超声可以提高药物在生物膜中的渗透效应，从而更好地发挥杀菌作用。具有很好的临床应用前景。本文对低频超声对牙菌斑生物膜促渗作用的研究进展作一综述。

关键词: 牙菌斑生物膜, 低频超声, 促渗

Abstract: A plaque biofilm is a bacterial biofilm that is a soft, unmineralized bacterial population that is encased in a matrix that adheres to each other, or adheres to the surfaces of teeth, interdentals or prostheses and can not be washed away by water. It is an independent micro-ecological environment with structural, morphological, and metabolic activities, and its resistance is many times that of plankton. The researchers found that low-frequency ultrasound can improve the penetration of drugs in biofilms, so as to better play a bactericidal effect. It has a good clinical application prospects. This article reviews the research progress of low-frequency ultrasound on the permeation of dental plaque.

Key words: plaque biofilm, low-frequency ultrasound, permeation

中图分类号:

R781.4

马巍王涛. 低频超声对牙菌斑生物膜促渗作用的研究进展[J]. , 2019, 39(2): 179-182.

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