›› 2019, Vol. 39 ›› Issue (8): 748-752.
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曹国琴,林江
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摘要： B10细胞（IL-10 producing B cell）通过分泌IL-10或表达CD1d\\CD80\\CD86\\FasL等调控机体免疫，其在自身免疫性疾病及感染性疾病中起着重要的免疫调控作用。近来有研究表明，局部药物诱导牙龈组织中B10细胞表达及移植B10细胞均能抑制牙周炎症及牙槽骨吸收。因此,探讨B10细胞在牙周炎中的作用将有助于牙周炎的治疗研究。
关键词: B10细胞, 牙周炎, 免疫抑制
Abstract: B10 cell（IL-10 producing B cell）exerts significant immunomodulatory effects through the production of interleukin (IL)-10 and the expression of CD1d, CD80, CD86, FasL. It plays an important immunomodulatory role in autoimmune diseases and infection disease. Recent studies show that local induction of the expression of B10 cell and adoptive transfer of B10 cell can alleviate inflammation of periodontal tissue and alveolar bone resorption. Thus, the research on the function of B10 cell in periodontitis will be of great help for the further study on the therapy of periodontal diseases.
Key words: B10 cell, periodontitis, immune tolerance
中图分类号:
R781.4
曹国琴 林江. B10细胞与牙周炎免疫调控的研究进展[J]. , 2019, 39(8): 748-752.
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