测试人牙周膜粘弹性力学特性的纳米压痕实验条件研究

›› 2020, Vol. 40 ›› Issue (4): 313-318.

测试人牙周膜粘弹性力学特性的纳米压痕实验条件研究

施昊天¹,鹿如鑫²,刘鑫²,刘懋¹,黄辉祥³,吴斌⁴,严斌¹

1. 南京医科大学附属口腔医院
2. 东南大学机械工程学院
3. 南京工程学院机械工程学院
4. 南京林业大学机械电子工程学院

收稿日期:2019-10-11 修回日期:2019-11-21 出版日期:2020-04-28 发布日期:2020-04-28
通讯作者: 严斌 E-mail:byan@njmu.edu.cn
基金资助:
国家自然科学基金;国家自然科学基金;江苏省重点研发计划专项资金项目资助课题;江苏省高校自然科学基金;江苏高校优势学科建设工程资助项目课题

Study on the experimental conditions of nano-indentation test for investigating the viscoelastic properties of human periodontal ligament

Received:2019-10-11 Revised:2019-11-21 Online:2020-04-28 Published:2020-04-28

摘要/Abstract

摘要： 目的：研究通过纳米压痕实验测试人牙周膜粘弹性性能的实验条件。方法：预备人牙周膜样本，在保湿环境下使用平头压头对人牙周膜分别进行基于纳米压痕的蠕变实验和约化弹性模量测试。根据控制变量法设置实验方案，测试不同实验条件对实验结果的影响。结果：最佳实验参数范围：基于纳米压痕的蠕变实验的加载率为0.3-0.5mN/s；基于纳米压痕的约化弹性模量测试的保载时间为25s和峰值载荷为2-3mN。并得到了人牙周膜的纳米压痕蠕变曲线和0.0121-6.84 MPa的约化弹性模量范围。结论：验证了人牙周膜具有粘弹性性质，并提出了适用于人牙周膜纳米压痕实验的条件。

关键词: 纳米压痕, 粘弹性, 牙周膜, 生物力学

Abstract: Objective：To design experimental conditions via nano-indentation test, in order to investigate the viscoelastic properties of the human periodontal ligament（PDL）. Methods：After preparation of human PDL samples, the nano-indentation creep test and conventional reduced elastic modulus test were carried out by a flat punch in a moistful environment. The experimental scheme was set up according to the control variable method, and the influence of different experimental conditions on the experimental outcomes were analyzed. Results：The optimum parameters were obtained as follows: the nano-indentation creep test demanded the loading rate as 0.3-0.5 mN/s; the holding time of 25s and peak load of 2-3 mN were suitable for the conventional nano-indentation test. The nano-indentation creep curve of human periodontal ligament and the reduced elastic modulus range of 0.0121-6.84 MPa were obtained. Conclusion：The viscoelastic properties of human periodontal ligament were verified. We obtained the experimental conditions that were applicable to nano-indentation test for human periodontal ligament.

Key words: Nano-intendation, Viscoelastic, Periodontal ligament, Biomechanics

中图分类号:

R783.5

施昊天鹿如鑫刘鑫刘懋黄辉祥吴斌严斌. 测试人牙周膜粘弹性力学特性的纳米压痕实验条件研究[J]. 口腔医学, 2020, 40(4): 313-318.

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