巨噬细胞极化在种植体周围组织愈合的作用及研究进展

摘要/Abstract

摘要： 牙科种植体植入牙槽骨后会先引起机体的异物反应，而后转向修复过程。巨噬细胞在该转化过程中起着关键作用。近年来，众多研究表明通过调控种植体周围的巨噬细胞可促进种植体周围软硬组织的愈合，然而巨噬细胞在其中所起的具体作用及机制却鲜有详尽的报道。该文就现有的相关研究，对巨噬细胞极化在种植体周围组织愈合中所发挥的作用及机制作一综述。

关键词: 口腔种植, 巨噬细胞极化, 伤口愈合, 骨结合, 种植体周围疾病

Abstract: The dental implant inserted into the alveolar bone initially triggers the foreign body reaction and then turns to healing process, which is primarily mediated by macrophages. Recently, most studies about macrophages have discovered that regulating macrophages can promote the wound healing of soft and hard tissues around the implant. However, the specific roles and mechanism of macrophages during this process are rarely reported. In this article, the related studies trying to reveal the effect and mechanisms of macrophages during the healing process of peri-implant were reviewed.

Key words: dental implant surgery, macrophage polarization, wound healing, osteointegration, peri-implant disease

中图分类号:

R782.1

张艺张晓梦史俊宇赖红昌. 巨噬细胞极化在种植体周围组织愈合的作用及研究进展[J]. 口腔医学, 2020, 40(7): 644-647.

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